(8) Cerebral Palsy Flashcards
What is cerebral palsy?
- involves a disorder of mvmt and posture
- permanent but not unchanging
- due to non progressive interference
- interference in developing brain
What are the risk factors for CP (6)?
- prematurity
- low birth rate
- TBI
- infection
- placenta complications
- complications @ birth
What are causes of CP?
- Periventricular Leukomalacia (PVL)
- Intraventricular Haemorrhage (IVH)
- Hypoxic-Ischaemic Encephalopathy (HIE)
What is Periventricular Leukomalacia?
- damage to the white matter
- damage to myelin, slowing and impeding nerve transmission
What are the major factors in periventricular leukomalacia?
- decreased blood (ischaemia) or O2 (hyoxia) flow to PV region
- Hypoxic-ischaemic incidents damage to the blood brain barrier (BBB)
What does the blood brain barrier do?
- regulates flow of nutrients to brain
- supports neurons throughout nervous sysetm
What are the risk factors for PVL (7)?
- premature birth 26 weeks
- low birth weight (1500g)
- intrauterine infection
- infection around time delivery
- placental blood vessel conditions
- vaginal bleeding
- hypotension, hypoxaemia
When may an intraventricular haemorrhage occur?
PVL may be accompanied by a haemorrhage or bleeding in the periventricular-intraventricular area
What happens in the brain in a PVL?
- enlarged ventricles
- loss white matter
What happens in the brain in an IVH?
- bleeding in ventricles
- injury white matter
- cell damage
How does an intraventricular haemorrhage occur?
- most common 48hrs birth
- changes BP cause delicate blood vessels rupture
- results loss O2 to tissue
- swelling & obstruction can lead to hydrocephalus
What are risk factors for IVH (6)?
- premature birth
- low birth weight
- placental blood clots
- weak blood vessels brain
- maternal high BP or infection
- shaken baby syndrome
What causes hypoxic-ischemic encephalopathy?
- O2 deprivation to the brain
- if lasts too long, brain tissue destroyed
What are impairments that can be seen as a result of hypoxic-ischemic encephalopathy (5)?
- epilepsy
- developmental delay
- motor impairment
- neurodevelopmental delay
- cognitive impairment
What areas of the brain will mild hypoxia affect?
parasagittal white matter
What areas of the brain will severe hypoxia affect?
- putamen
- thalamus
- paracentral white matter
What are the risk factors for hypoxic-ischemic encephalopathy?
- acute maternal hypotension
- blood containing less O2
- cardiac complications
- pressure to cranium changing its shape
- impaired blood flow to brain
- injury from umbilical cord complications
How is CP diagnosed?
- MRI
- Medical Hx
- Reflexes
- Motor skills Ax
- Differential diagnosis
What are the two types of spastic CP?
- Bilateral spastic CP
- Unilateral spastic (hemiplegia) CP
What are features of Spastic CP?
- increased tone
- increased reflexes
- pyramidal signs (Babinski)
- abnormal pattern movement & posture
What are the two types of Dyskinetic CP?
- Dystonic
- Choreo-athetotic
What are features of dyskinetic CP?
- involuntary, uncontrolled, recurring movements
- primitive reflex patterns
- muscle tone varying