7.3.5 Acylation Flashcards

1
Q

How are acyl chlorides made?

A
  • Substituting a Cl atom for the OH group
  • In a carboxylic acid
  • oyl Chloride
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2
Q

How are acid anhydrides made?

A
  • Substitution of OH group in a carboxylic acid
  • With an alkanoate
  • oic anhydride
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3
Q

What reactions do acyl chlorides undergo?

A
  • Nucleophilic addition-elimination reactions
  • Eg. Hydrolysis, alcohols -> Esters, forming amides
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4
Q

How does hydrolysis of Acyl chlorides work?

A
  • Forms carboxylic acid and HCL
  • Nucleophilic addition-elimination reaction
  • H2O added across C=O bond
  • HCl eliminated
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5
Q

How does formation of esters work from acyl chlorides?

A
  • React Acyl chlorides with Alcohols
  • Forming esters
  • Nucleophilic addition-elimination reaction
  • OH adds across C=O bond
  • HCL eliminated
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