7.3 stem cells Flashcards
Stem cell
An unspecialised cell that can divide by mitosis repeatedly and differentiate into specialised cells
Embryonic stem cell
Pluripotent
Stem cells that can divide and differentiate into any specialised tissues
Adult tissue stem cells
Multipotent
Stem cells that are involved in the repair and replacement of specialised cell eg. Blood and skin
Totipotent cells
Can make all specialised cell types. Including extra embryonic cells (placenta/umbilical cord)
Found in Morula/zygote
Pluripotent cells
Can make all specialised cell types but ot extra embryonic cell types
Found in blastocyst
Multipotent cells
Can make a restricted range of cell type e.g. haemopoietic stem cells
Fond in enveloping embryo too
Adult stem cell: nature and uses
Can divide to make more of themselves
Multipotent
Adult stem cell: positives
Easily obtained
Won’t be rejected: same DNA as recipient
Adult stem cell: negatives
Not pluripotent
Embryonic stem cell: nature and uses
Taken from embryo
From blastocyst (4-5 days)
Morula stem for totipotent
Embryonic stem cell: positive
Pluripotent: any cell type
Embryonic stem cell: negatives
Rejected by immune system
Can lead to cancerous growth
Destruction of foetus/ artificial nature of conception leads to ethical issues
Umbilical cord ES stem cells: nature and uses
Umblical chord: from foetus
Umbilical cord ES stem cells: positives
Can be frozen for later in life
Avoids ethical issues
Umbilical cord ES stem cels: negatives
Logistically hard and expensive
Little evidence of efficacy