7. The Chemical Senses Flashcards
What is JND?
Just Noticeable Difference: The detection threshold of the concentration of odorants.
What is identification of odours like without visual cues?
Poor, but when given a choice of options the performance is often perfect. This shows how important contextual information is.
What’s the relationship with smoking and identifying odours
Negative relationship
What’s the relationship with age and identifying odours?
Relatively constant until 70 where there is a steep drop off.
How many types of olfactory receptor neurones (ORN) are there?
350
How many types of olfactory receptor neurones (ORN) are there?
350
How many of each olfactory receptor neurones (ORN) are there?
10,000-20,000
What are GPCRs
G-protein coupled receptors
How does the olfactory system work?
- Odorant molecules dissolve into mucus
- Bind to olfactory receptors
- Open calcium and sodium channels resulting in their influx
- If the concentration of odorant molecules is high enough the membrane will depolarise resulting in an action potential
- AP goes to glomeruli in the olfactory bulb
- AP then goes to higher cortical areas.
What is the piriform cortex known as?
The primary auditory cortex
What does the piriform cortex do in the olfactory system?
- Receives signals from olfactory bulb
- Anterior piriform cortex: produces representations of features of the chemical structure of odorants.
- Posterior piriform cortex: produces representations of the quality of an odour overall.
What does the piriform cortex do in the olfactory system?
- Receives signals from olfactory bulb
- Anterior piriform cortex: produces representations of features of the chemical structure of odorants.
- Posterior piriform cortex: produces representations of the quality of an odour overall.
- After repeated neural activation related to the same odour, neural connections can form between each component.
What does the amygdala do in the olfactory system?
- Activated by emotional stimuli such as pleasant and unpleasant smells
- Sends signal to hypothalamus
What does the entorhinal cortex do in the olfactory system?
- Gateway to the hippocampus (memory)
What does the orbitofrontal cortex do in the olfactory system?
- Receives signals from the amygdala (emotions), piriform cortex (representations of odour) and entorhinal cortex (hippocampus gateway).
- Evaluates incoming stimuli as positive or negative.