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Peripheral Neural Transmission > 7. NANC Transmission > Flashcards

7. NANC Transmission Flashcards

1
Q

Dipyridamole

A

Blocks adenosine uptake into cells, prolonging its action

Also inhibits PDE V - used as an inodilator in heart failure

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2
Q

ADMA (asymmetric dimethyl arginine)

A

Endogenous Non specific NOS inhibitor
Increased in hypercholesteraemia and renal failure
Feedback regulator?

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3
Q

Nitroglycerin (glyceryl trinitrate)

A

NO donor

Treat angina

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4
Q

Sildenafil

A

Selective PDE V inhibitor
Prevents cGMP breakdown
Promotes vasodilation -> treats erectile dysfunction
Used as an inodilator in heart failure

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5
Q

Caffiene

A

Blocks the A1 adenosine GPCR, found on presynaptic terminals inhibiting neurotransmitter release and promoting sleep

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Peripheral Neural Transmission (8 decks)

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