7- How pathogens evade the immune response Flashcards
What are virokines and viroceptors
Proteins that are made by bacteria that mimic cell receptors/ cytokines - act as a decoy
What do bacterial capsules do?
Cover proteins on bacteria - less likely to be recognised for phagocytosis
What is viral latency
Virus stays latent in body and surface antigens change in order to not be recognized
Shut of replication - evade detection
Name a bacterial mechanism of evading the immune response.
Virokines
Bacterial capsule
Viral latency
Infecting immune-privileged tissues
Name a mechanism that pathogens use to attack the immune system
Infect and kill immune cells
Down regulate/inhibit immune effector molecules (cytokines)
Inhibit/up-regulate cell signalling pathways
Name the 2 ways that bacteria evade the immune system through antigenic variation
antigenic drift
reassortment- antigenic shift