7- Different types of vaccines Flashcards
Why do we vaccinate
Prevent diseases
disease eradication
Describe the perfect vaccine
Strong, lifelong, appropriate immune response in the correct place
Safe, cheap, easy to administer
What are the 6 different types of vaccines
Inactivated
Live attenuated
Subunit
Vectored
DNA
mRNA
Describe a inactivated vaccine
Vaccine composed of the dead pathogen- inactivated by harsh chemicals so it cannot replicate
Describe a live attenuated vaccine
vaccine in which microorganism loses its pathogenicity (can’t cause disease) but can still replicate in the host
Describe a sub-unit vaccine
live attenuated vaccine that only includes the antigens that best stimulate the immune system
Describe a vectored vaccine
insert the gene that expresses the proteins of the virus but it can not replicate
Describe a DNA vaccine
a vaccine that is made from the DNA of a pathogen and that does not have disease-causing capabilities
Which vaccine has the effect that if multiple boosters are needed it could wipe out the vaccine
Vectors- immunity to the backbone so sometimes need to use different vaccines
What is an adjuvant
Adjuvants are pharmacological additives that enhance the body’s natural immune response to an antigen
Ensures the vaccine is not swept away immediately
Benefits of inactivated vaccines
Made rapidly - safe for immunocompromised patients
Which type of vaccine often has a poor immune response to it
subunit (only 1 protein)
What is a limitation of inactivated vaccines
typically short duration of immunity
Which vaccine has the potential to reverse to virulence
Live attenuated
What is a pro of DNA vaccine
good T-cell mediated immunity
difficult to get a strong Ab response
