7 Electrolytes and Vitamins Flashcards
Sodium function:
Blood pressure, maintaining plasma volume
Potassium function:
Blood pressure, reducing kidney stone risk, potentially reducing bone loss.
Sulphur function:
Amino acid component, glutathione component
Thiamin function:
Coenzyme in CHO and branched chain amino acid metabolism (TPP)
Riboflavin function:
Coenzyme in oxidation reduction reactions
Niacin function:
Cosubstrate and coenzyme for transfer of hydride ion
B6 function:
Coenzyme in metabolism
Folate function:
Coenzyme in methyl transfers
B12 function:
Coenzyme to convert homocysteine to methionine and CoA to succinyl CoA
Biotin function:
Coenzyme in bicarbonate dependent carboxylation reactions
Choline function:
Precursor for acetylcholine, phospholipids, and betaine
Pantothenic acid function:
Component of CoA and phosphopantetheine (fat metabolism)
Vitamin c function:
Cofactors for biosynthesis of collagen, carnitine, and neurotransmitters. Anti oxidant
Vitamin A function:
Vision, gene expression, reproduction, embryonic development, growth, immune function
Vitamin E function:
Anti oxidant. Prevent propagation of lipid peroxidation
Vitamin D
Anti proliferation and pro differentiation effects, enhances absorption of calcium and phosphorous
Vitamin k
Blood coagulation, bone metabolism
Do potassium requirements change during pregnancy? Why or why not?
No
Do sodium requirements change during pregnancy? Why or why not?
No
Do sulphur requirements change during pregnancy? Why or why not?
No
Do thiamin requirements change during pregnancy? Why or why not?
Yes, growth and increased E utilization
Do riboflavin requirements change during pregnancy? Why or why not?
Yes, growth and increase E utilization. Reduce urinary excretion to conserve also.
Do niacin requirements change during pregnancy? Why or why not?
Yes, increased E utilization
Do B6 requirements change during pregnancy? Why or why not?
High fetal and placental uptake, requirements increase towards end of pregnancy because no way to store so demand must be met with intake
Do folate requirements change during pregnancy? Why or why not?
Yes, high nucleotide synthesis and cell division
Do B12 requirements change during pregnancy? Why or why not?
Yes, only newly absorbed B12 is readily transported across placenta so can’t meet the need using stores.
Do biotin requirements change during pregnancy? Why or why not?
No. Compensate with absorbing more and excreting less
Do choline requirements change during pregnancy? Why or why not?
Yes, especially during embryogenesis, deplete maternal stores and large amounts delivered to the placenta
Do pantothenic acid requirements change during pregnancy? Why or why not?
Yes, no info but presume and round up
Do vitamin C requirements change during pregnancy? Why or why not?
Yes, especially with smokers
Do vitamin D requirements change during pregnancy? Why or why not?
No, little is transferred
Do vitamin E requirements change during pregnancy? Why or why not?
No
Do vitamin K requirements change during pregnancy? Why or why not?
No
What is the basis for thiamin DRI?
Erythrocyte transketolase activity,
Concentration in blood, urinary concentration
What is the basis for riboflavin DRI?
Erythrocyte glutathione reductase activity, RBC concentration, urinary excretion
What is the basis for niacin DRI?
Urinary excretion of niacin metabolites
What is the basis for B6 DRI?
Maintenance of blood 5’-pyridoxal phosphate levels.
What is the basis for folate DRI?
Erythrocyte folate, blood homocysteine and folate concentrations
What is the basis for B12 DRI?
Haematological status and normal blood values
What is the basis for biotin DRI?
Just AI
What is the basis for choline DRI?
Serum alanine aminotransferase activity (prevents liver damage)
What is the basis for pantothenic acid DRI?
Intake adequate to replace urinary excretion
What is the basis for vitamin C DRI?
Near maximal neutrophil concentration with minimal urinary excretion
What is the basis for vit A DRI?
Maintenance of body pool (RAE = 1/2 RE)
What is the basis for vitamin D DRI?
Serum concentration
What is the basis for vitamin E DRI?
Only made for alpha. Correlation between H2O2 induced erythrocyte lysis.
What is the basis for vitamin K DRI?
Just AI