5: Energy and protein Flashcards

0
Q

Basal metabolic rate.

A

Minimum energy expenditure compatible with life.

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1
Q

Estimated energy requirement (EER) definition and criteria.

A

Average energy intake for a healthy person of a given gender, age, weight, height, and activity level, consistent with good health. Criteria is body weight within the healthy range and in a non-growth state.

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2
Q

Basal energy expenditure.

A

Kcal/24 hrs measured in the sedentary supine position.

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3
Q

Total energy expenditure (TEE)

A

Energy spent, on average, in a 24 hr period by an individual or a group of individuals.

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4
Q

Physical activity level (PAL)

A

TEE/BEE. Used only for adults and non pregnant non lactating women.

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5
Q

Sedentary (in terms of PAL)

A

Only the physical activity level that is required for independent living.

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6
Q

What is the strongest predictor of BEE?

A

Fat-free mass (FFM).

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7
Q

Why does BEE increase during pregnancy?

A

Metabolic contributions of the fetal placental unit + uterus, increase work of the heart and lungs, increased FFM (blood volume, skeletal mass, and fetal/uterine tissue).

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8
Q

What increase in energy is required by just the fetus, on average, over the whole pregnancy? Does the rate change through the pregnancy?

A

56 kcal/kg body weight/day. By the end of the pregnancy the fetus accounts for half of the increment of increased energy demands. Much higher than the beginning of the pregnancy.

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9
Q

What is the average energy deposition during pregnancy? Does it vary?

A

Average is 41,518 kcal. Can be closer to 60,726 in lower BMIs and in very high BMIs can be -324.

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10
Q

Why does PAL decrease during pregnancy?

A

Primarily due to increase in BEE (PAL= TEE/BEE).

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11
Q

What is the median increase in TEE during pregnancy?

A

8 kcal/gestational week. Ex 2nd trimester 169 kcal, 3rd trimester 272 kcal to keep up with increase in TEE.

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12
Q

How many calories can be attributed to energy deposition per day throughout pregnancy?

A

180 kcal/day

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13
Q

How much protein is needed per day on average? What is this amount compensating for?

A

50 g/day, because constant degradation and synthesis of protein is not 100% efficient and starts to deplete.

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14
Q

Does the rate of protein synthesis change throughout the life cycle?

A

In g/kg/day rate different in newborns (17.4), infants (6.9), adults (3), elderly (1.9)

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15
Q

What accounts for the additional protein requirements in pregnancy?

A

Supporting growth of fetal and maternal tissue and maintenance of additional protein stores (important in latter pregnancy)

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16
Q

What is the RDA for protein for pregnant women?

A

35 g/day in additional to the 0.8 g/kg/day

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17
Q

What indicators are used to estimate protein RDA?

A

Nitrogen equilibrium

18
Q

Are the recommendations for alpha linolenic acid and linoleic acid RDA or AI? What is the significance of that?

A

AI. This is just the median intake associated with good health outcomes, so not perfect.

19
Q

What is the carbohydrate RDA based on?

A

The minimum amount of glucose required by the brain without needing to use fat or protein as an energy source.

20
Q

Histidine

A

Indispensable. Higher requirements in infants.

21
Q

Alanine

A

Dispensable.

22
Q

Arginine

A

Conditional. Glutamine/glutamate and asparagus are precursors.

23
Q

Aspartic acid

A

Dispensable

24
Q

Isoleucine

A

Indispensable.

25
Q

Leucine

A

Indispensable

26
Q

Tyrosine

A

Conditional. Phenylalanine is precursor.

27
Q

Serine

A

Dispensable

28
Q

Tryptophan

A

Indispensable

29
Q

Valine

A

Indispensable

30
Q

Aspargine

A

Dispensable

31
Q

Cysteine

A

Conditional. Methionine and serene precursors. Higher requirement for premature babies, inadequate rate of synthesis from methionine.

32
Q

Proline

A

Conditional. Glutamate precursor.

33
Q

Methionine

A

Indispensable

34
Q

Phenylalanine

A

Indispensable

35
Q

Glutamic acid

A

Dispensable

36
Q

Lysine

A

Indispensable

37
Q

Glycine

A

Conditional. Serene and choline precursors.

38
Q

Glutamine

A

Conditional. Glutamic acid and ammonia precursors. Higher requirements in conditions of stress.

39
Q

What does “conditionally indispensable” mean?

A

They are synthesized from other amino acids and/or their synthesis is limited under special pathophysiological conditions.

40
Q

It is thought they probably only these five amino acids are truly dispensable to a neonate:

A

Alanine, aspartate, glutamate, serine, and probably asparagine

41
Q

What are the two nitrogen pools?

A

All proteins in tissue and circulation, free amino acids dissolved in body fluids, from dietary intake, and de novo synthesis

42
Q

How much protein in an adult human being is synthesized and degraded each day (on average)?

A

250 g protein.

43
Q

What parts of pregnancy is protein stored? Mobilized?

A

Stored early, mobilized in second half.