7 - David Nicholls (Indigenous man with MI trying to rescue grandkids from lake)

Question 1

symptoms (5)?

Answer 1

chest pain possibly radiating to jaw and left arm. SOB. Sweaty. Nausea, light-headedness

Question 2

MOA of SOB in MI

Answer 2

Myocardial infarction -> impaired contractility -> dec cardiac output -> inc end diastolic volume -> inc end diastolic pressure in L ventricle -> inc L atrial pressure -> inc pulmonary pressure -> pulmonary hypertension -> pulmonary congestion -> shortness of breath

Question 3

which coronary arteries are responsible for each part of heart

Answer 3

LAD - anteroseptal and anteroapical
Right - Inferior and posterior
Circumflex - Anterolateral

Question 4

biochemical markers in MI? when do they peak?

Answer 4

tropinin - peaks at 48 hrs (system 1 week)

Creatine Kinase MB - peaks at 24 hrs (system 3 days)