7 - Chemistry 1

Question 1

effect of posture on lab test results

Answer 1

these dec when supine: protein, albumin, lipids, iron, ca, enzymes, ig, thyroxine

Question 2

gray top tube

Answer 2

contains NaF, potassium oxalate, or sodium iodoacetate

used to stabilize glucose in plasma

Question 3

blue top tube

Answer 3

contains citrate (anti coag)
vol of blood that goes in is important b/c of ratio to citrate - used in coag studies

Question 4

specimens for what tests (4) should be put on ice immediately

Answer 4

lactate
ammonia
acid phosphatase
plasma catecholamines

Question 5

strenuous exercise increases and decreases which labs?

Answer 5

inc: acid phosphatase, ALT, AST, creatinine, phosphorus, CK
dec: iron, lipids, K

Question 6

5 lab tests that have diurnal variation

Answer 6

cortisol
renin
TSH
insulin
catecholamines

Question 7

which test - high sens or high spec - is used for population screening?

Answer 7

high sens - esp when disease is serious, treatable, and false pos does not lead to serious trauma to pt

Question 8

which test - high sens or high spec - is used for population screening when the disease is not treatable?

Answer 8

high spec - false pos cause a lot of psychological/economic trauma for much less benefit

Question 9

PPV, NPV

Answer 9

tp / (tp+fp), tn / (tn+fn)

Question 10

serum protein electrophoretic analysis used to dx

Answer 10

multiple myeloma

Question 11

csf electrophoresis can be used to detect

Answer 11

MS, neurosyphilis, subacute sclerosing panencephalitis

Question 12

best screening test for thyroid problems

Answer 12

TSH

Question 13

how do you calc LDL?

Answer 13

total cholesterol - (HDL + 1/5 TGs)