2 - Blood Component Therapies Flashcards
Which of the following is a property of ABO
blood group?
A. They are protein structure on RBC surface
B. Anti-A/B antibodies can only be acquired through
past transfusion or pregnancy
C. Native anti-A / B antibodies is present at birth
D. ABO share a common basic carbohydrate
structure
D
ABO antigens are modifications of ____
H substance
Can a pt w/ A neg blood get platelets that are AB pos? If yes, what complication would you be most worried about?
yes
Rh immunization/sensitization
Which of the following is a true statement?
A. Screen can pick up Anti-A / B antibodies that is
resulted from mistransfusion (A>B)
B. Crossmatch is performed before all blood product
is released
C. A positive screen may suggest a passively
acquired antibody
D. The principle of screeng and crossmatch is based on a chemical reaction
c
forward vs reverse blood typing
forward - use pt’s cells
reverse - use pt’s plasma
preop blood bank workup for pt about to undergo hip replacement w/ history of several transfusions and one “reaction”
type and screen
History obtained from previous hospital showed
patient has previously ID’ed antibody (Jka).
However, now antibody is no longer active. What
would you do?
A.Crossmatch and hold 2 units of compatible RBC
B.Nothing transfusion with O negative blood when
needed
C.Collect units from siblings
D.Order antigen (Jka) negative RBC units and hold in blood bank
d
what does the screen part of “type and screen” check for?
clinically significant non-naturally occurring antibodies against RBC antigens
usually acquired through past transfusion or pregnancy
crossmatching
done for ALL RBC transfusions that aren’t emergencies
check’s specific RBC unit w/ patient’s serum
blood is then set aside on hold for that specific patient
how long can blood be kept out of the blood bank not cooled?
30 min
best course of action for slightly elevated INR prior to surgery
do nothing - giving FFP is unlikely to help
Which of the following is an appropriate use
of FFP?
A. To reverse heparin overdose
B. To reverse a INR of 1.4 (nl 1.2)
C. To use for volume expansion in adult patients
D. To provide protein S in a patient with congenital
protein S deficiency
d
indications for FFP
coagulopathy due to multiple factor deficiencies (liver failure, vit K def, warfarin OD)
congenital clotting deficiency w/ no other way to give them that factor (F 2, 5, 10, 11, proteins C and S)
plasma exchange for TTP/HUS
