7. Cell Signaling | November 06, 2024 Flashcards

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1
Q

Signal molecules are the

A

Ligands

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2
Q

The two types of receptors

A
  1. Cell Surface Receptors
  2. Intracellular Receptors
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3
Q

Types of cell surface receptors

A
  1. Ion-channel linked receptor
  2. G-protein linked receptor
  3. Enzyme-linked receptor
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4
Q

Types of signals

A
  1. Lipid soluble
  2. Water soluble
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5
Q

Types of receptors

A
  1. Cell surface
  2. Intracellular
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6
Q

Types of cell surface receptors

A
  1. Ion channel linked
  2. GPCR —> G Protein
  3. Enzyme linked
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7
Q

Types of secondary messengers

A
  1. cAMP —> PKA
  2. cGMP —> PKG
  3. IP3 & DAG —> Kinase
  4. Ca2+ —> Calmodulin
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8
Q

The IP3 secondary messenger forms

A

the hydrophilic heads of the phospholipid molecule

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9
Q

The DAG secondary messenger forms

A

the two fatty acid tails of the phospholipid molecule

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10
Q

Passing the signal multiple times within the cell yields what outcome?

A

The signal is amplified significantly based on the number of times the signal is passed along the pathway to different proteins

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11
Q

There are two main signaling pathways

A
  1. Fast pathway: expressed enzyme being activated for function; a pathway that activates already existing proteins for function
  2. Slow pathway: transcriptional factor of proteins; more powerful pathway that amplifies the amount and effect of the proteins
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12
Q

How are signals passed from protein to protein (considering the molecular passage of signals)

A
  1. Phosphorylation: giving the protein (mostly downstream proteins) molecule the phosphate group
  2. Conformational change:
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