7. Cell Signaling | November 06, 2024 Flashcards
1
Q
Signal molecules are the
A
Ligands
2
Q
The two types of receptors
A
- Cell Surface Receptors
- Intracellular Receptors
3
Q
Types of cell surface receptors
A
- Ion-channel linked receptor
- G-protein linked receptor
- Enzyme-linked receptor
4
Q
Types of signals
A
- Lipid soluble
- Water soluble
5
Q
Types of receptors
A
- Cell surface
- Intracellular
6
Q
Types of cell surface receptors
A
- Ion channel linked
- GPCR —> G Protein
- Enzyme linked
7
Q
Types of secondary messengers
A
- cAMP —> PKA
- cGMP —> PKG
- IP3 & DAG —> Kinase
- Ca2+ —> Calmodulin
8
Q
The IP3 secondary messenger forms
A
the hydrophilic heads of the phospholipid molecule
9
Q
The DAG secondary messenger forms
A
the two fatty acid tails of the phospholipid molecule
10
Q
Passing the signal multiple times within the cell yields what outcome?
A
The signal is amplified significantly based on the number of times the signal is passed along the pathway to different proteins
11
Q
There are two main signaling pathways
A
- Fast pathway: expressed enzyme being activated for function; a pathway that activates already existing proteins for function
- Slow pathway: transcriptional factor of proteins; more powerful pathway that amplifies the amount and effect of the proteins
12
Q
How are signals passed from protein to protein (considering the molecular passage of signals)
A
- Phosphorylation: giving the protein (mostly downstream proteins) molecule the phosphate group
- Conformational change: