3. Plasma Membrane - Class 2 - 09/09/2024 Flashcards

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1
Q

Integral proteins are also called

A

Trans-membrane proteins

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2
Q

The lipid bilayer is about

A

5 nm

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3
Q

Characteristics of plasma membrane

A
  1. Fluidity
  2. Asymmetry
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4
Q

Composition of plasma membrane

A
  1. Membrane lipids (continuous double layer)
  2. Membrane proteins
  3. Membrane carbohydrates
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5
Q

Control and regulate the stability of the plasma membrane

A

Cholesterol

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6
Q

Types of membrane proteins by function

A
  1. Transporters
  2. Linkers
  3. Receptors
  4. Enzymes
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7
Q

Types of membrane proteins by binding patterns

A
  1. Integral proteins
  2. Peripheral proteins
  3. Lipid-linked proteins (rests peripherally, but can bind to lipids of the membrane by non-covalent bonds)
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8
Q

Fluidity of lipid molecules in lipid bilayer

A
  1. Lateral diffusion (easiest)
  2. Flip-flop (most difficult - requiring a lot more energy)
  3. Rotation
  4. Flexion
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9
Q

Factors affecting fluidity of membrane lipids

A
  1. Saturation degree of hydrocarbon tail
  2. Length of hydrocarbon tail
  3. Dual regulatory role of cholesterol
  4. Ratio of lecithin vs sphingomyelin
  5. Influence of membrane proteins
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10
Q

Highest frequency lipid movements of lipid membrane
&
The only movements possible by membrane proteins

A
  1. Lateral diffusion
  2. Rotation
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11
Q

FRAP means

A

Fluorescence recovery after photobleaching

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12
Q

FLIP means

A

Fluorescence loss in photobleaching

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