7: AIDS

Question 1

HIV is a _____ disease more frequently than women, due to men who have sex with men. There is a resurgence of cases in men who have sex with men due to _____ sex.

Answer 1

HIV is a male disease more frequently than women, due to men who have sex with men. There is a resurgence of cases in men who have sex with men due to unprotected sex.

Question 2

From infection to AIDS is about _____ – _____ yrs.

CD4 count can can drop in any normal infection, so we can never make any conclusions based on _____ count.

We diagnose HIV with the presence of anti HIV _____.

Answer 2

From infection to AIDS is about 9.5 – 10.5 yrs.

CD4 count can can drop in any normal infection, so we can never make any conclusions based on CD4 count.

We diagnose HIV with the presence of anti HIV antibodies.

Question 3

If you wait till 350 CD4 to do treatment people do well, but if you start treatment @ _____ CD4 some people will do better.

Answer 3

If you wait till 350 CD4 to do treatment people do well, but if you start treatment @ 500 CD4 some people will do better.

Question 4

Potential Concerns about Early Antiretroviral Therapy:

ARV-related _____

_____-adherence to ART

Drug _____

Cost

Answer 4

Potential Concerns about Early Antiretroviral Therapy:

ARV-related toxicities

Non-adherence to ART

Drug resistance

Cost

Question 5

For HIV ART, there are:

There are nucleoside _____ transcriptase inhibitors

There are non nucleoside _____ transcriptase inhibitors

There are integrase _____

There are fusion _____

There are protease _____

There are _____ inhibitors

Answer 5

For HIV ART, there are:

There are nucleoside reverse transcriptase inhibitors

There are non nucleoside reverse transcriptase inhibitors

There are integrase inhibitors

There are fusion inhibitors

There are protease inhibitors

There are CCR5 inhibitors: makes sense because CCR5 is first cofactor binding & that is why post exposure prophylaxis works

Question 6

The current status of all ART preferred treatment regimens is:

_____ nucloeside/nucleotide reverse transcriptase inhibitor

pluse only one of the following:

_____ non nucleoside reverse transcriptase inhibitors

or

_____ protease inhibitor

or

_____ integrase inhibitor

Answer 6

The current status of all ART preferred treatment regimens is:

2 nucloeside/nucleotide reverse transcriptase inhibitor

pluse only one of the following:

1 non nucleoside reverse transcriptase inhibitors

or

1 protease inhibitor

or

1 integrase inhibitor