7 Flashcards
What is the primary role of eosinophils?
Elimination of parasites and involvement in allergic inflammation
Eosinophils release toxic chemicals to combat parasites that are too large for phagocytosis.
How do eosinophils contribute to allergic inflammation?
They promote tissue inflammation by releasing toxic chemicals and may dampen inflammatory processes by breaking down histamine
This dual role helps to manage allergic reactions.
What substances do basophils contain that are associated with allergic reactions?
Heparin, histamine, and other inflammatory substances
These substances are released in response to allergens.
What triggers basophils to release their granule contents?
Binding of allergens to antibody-type receptors on the basophil membrane
This response is crucial for the rapid onset of allergic symptoms.
What is the function of mast cells in allergic reactions?
They release granule contents quickly upon allergen binding
This rapid release is responsible for swift allergic responses, like hay fever symptoms.
What types of leukocytes have a large nucleus and granules in their cytoplasm?
Monocytes and lymphocytes
These cells make up 25% to 50% of all leukocytes.
Where do monocytes originate and what do they develop into?
They originate in red bone marrow and develop into macrophages in tissues
Macrophages play a crucial role in the immune response.
What is interleukin 1 and what are its effects?
A cytokine that raises body temperature, stimulates globulin production, and enhances T-lymphocyte production
It acts on the hypothalamus during microbial infections.
What is the monocyte-macrophage system also known as?
The reticuloendothelial system
This system includes all the body’s monocytes and macrophages.
True or False: Eosinophils are the most active leukocytes in phagocytosis.
False
Neutrophils are more active in phagocytosis than eosinophils.
Fill in the blank: Basophils are closely associated with _______ reactions.
allergic
Their granules contain substances that promote inflammation during allergic responses.
What is the primary role of eosinophils?
Elimination of parasites and involvement in allergic inflammation
Eosinophils release toxic chemicals to combat parasites that are too large for phagocytosis.
How do eosinophils contribute to allergic inflammation?
They promote tissue inflammation by releasing toxic chemicals and may dampen inflammatory processes by breaking down histamine
This dual role helps to manage allergic reactions.
What substances do basophils contain that are associated with allergic reactions?
Heparin, histamine, and other inflammatory substances
These substances are released in response to allergens.
What triggers basophils to release their granule contents?
Binding of allergens to antibody-type receptors on the basophil membrane
This response is crucial for the rapid onset of allergic symptoms.
What is the function of mast cells in allergic reactions?
They release granule contents quickly upon allergen binding
This rapid release is responsible for swift allergic responses, like hay fever symptoms.
What types of leukocytes have a large nucleus and granules in their cytoplasm?
Monocytes and lymphocytes
These cells make up 25% to 50% of all leukocytes.
Where do monocytes originate and what do they develop into?
They originate in red bone marrow and develop into macrophages in tissues
Macrophages play a crucial role in the immune response.
What is interleukin 1 and what are its effects?
A cytokine that raises body temperature, stimulates globulin production, and enhances T-lymphocyte production
It acts on the hypothalamus during microbial infections.
What is the monocyte-macrophage system also known as?
The reticuloendothelial system
This system includes all the body’s monocytes and macrophages.
True or False: Eosinophils are the most active leukocytes in phagocytosis.
False
Neutrophils are more active in phagocytosis than eosinophils.
Fill in the blank: Basophils are closely associated with _______ reactions.
allergic
Their granules contain substances that promote inflammation during allergic responses.
