6.Learning,Memory and addiction

Question 1

Describe Putative role of long term potentiation in creating short term memories.

Answer 1

it helps to strengthen an existing synapse

Question 2

BE ABLE TO give an example of how ionotropic and metabotropic responses are important for the induction of long term potentiation

Answer 2

Ionotropic AMPA response and metabotropic NMDA response to glutamate occurs during induction of LTP

Question 3

Define synaptic plasticity

Answer 3

its when both short and long term memories are stored by altering synaptic activity within the brain

Question 4

Describe retrograde amnesia

Answer 4

Short term memory is lost. typical in a trauma to head, when you can’t remember the accident event

Question 5

Describe the anterograde amnesia

Answer 5

Short term memory is okay, but can’t consolidate or make long term memories.

Question 6

Describe how dementia is different than amnesia

Answer 6

Dementia is associated with impaired memory but also includes impaired cognition that amnesia doesn’t have.

Question 7

Describe the function of limbic system with respect to creation of emotions and motivation/reward systems

Answer 7

The limbic system has the amygdala that is important in emotional processing and negative emotions are generated as punishment and positive emotions are generated as motivational /reward system

Question 8

Describe the importance of dopamine in the brains reward system

Answer 8

the reward system is activated by the dopaminergic neurone so exogenous activation of this system with dopamine can give the feeling of well being

Question 9

Explain the cycle by which activities or drugs are thought to become addictive.

Answer 9

it goes from liking it to wanting it to needing it