69: Phylogeny and development of the digestive system Flashcards

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1
Q

What are the primary functions of the digestive system?

A

o Ingests and digests food.
o Absorbs nutrients from digested food.
o Removes undigested remnants from the body.

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2
Q

What are the major subdivisions of the digestive tract?

A

o Oral Cavity (Cavitas Oris): Initial site for food intake and digestion.
o Pharynx: Passageway for food moving from oral cavity to esophagus.
o Esophagus: Conducts food to the stomach.
o Stomach (Gaster, Ventriculus): Main site of digestion with acidic environment.
o Intestines (Small and Large): Absorbs nutrients; the large intestine absorbs water and forms feces.
o Anus or Cloaca: Excretes digested waste material.

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3
Q

What are the accessory organs of the digestive system and their functions?

A

o Tongue (Lingua): Aids in food manipulation and taste sensation.
o Teeth (Dentes): Involved in the mechanical breakdown of food.
o Oral (Salivary) Glands: Secrete enzymes that begin carbohydrate digestion.
o Liver: Produces bile, crucial for lipid digestion.
o Gallbladder: Stores and concentrates bile.
o Pancreas: Produces digestive enzymes and bicarbonate.

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4
Q

What is enzymatic digestion and how are enzymes activated?

A

o Digestive enzymes are hydrolases, secreted as inactive zymogens to prevent self-damage.
o Pancreatic enzymes are activated by entero kinase.
o Amylase, secreted by the pancreas (and in some mammals by salivary glands), breaks down starch.
o The increase in starch availability due to agriculture has influenced human dietary patterns.

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5
Q

How do protochordates feed and digest food?

A

o Feeding: Primarily filter feeders using a large pharynx with slits to trap food particles.
o Digestion: Movement of water and food facilitated by cilia.
o Liver Evolution: Originates as an outgrowth of the intestine.

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6
Q

What evolutionary changes occurred in vertebrates related to feeding?

A

o Pharynx: Became muscular, supporting a shift from filter feeding to predation.
o Feeding Mechanism: Reliance on cilia for moving food became impractical.

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7
Q

What are cyclostomes and gnathostomes, and how did teeth evolve?

A

o Cyclostomes: Represent the only surviving jawless vertebrates (agnathans).
o Gnathostomes (Jawed Vertebrates): Include all other extant vertebrates, featuring active predation advantages due to jaws.
o Teeth Evolution: Evolved alongside jaws, with cartilaginous fishes displaying true teeth homologous to placoid scales.

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8
Q

How did the stomach evolve in cartilaginous fishes?

A

o Predatory Adaptation: The evolution of the stomach is attributed to their predatory nature, allowing them to ingest large portions of food at irregular intervals.
o Functional Development: Initially served as a storage area for ingested solids, evolved to secrete hydrochloric acid (HCl) and pepsin for protein digestion.
o Pancreatic Development: Represents a novel feature in cartilaginous fishes, enhancing their digestive capabilities.

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9
Q

What is the derivation and formation of the digestive system in mammals?

A

o The digestive system originates from the endoderm, with mesodermal contributions for structural support, and terminal compartments covered by ectodermal epithelium.
o During gastrulation, the endoderm specifies and forms the primitive gut or archenteron, a hollow tube under the notochord.
o The blastopore, the initial opening, develops into the anus or cloaca, a primitive trait in vertebrates.

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10
Q

How is the primitive gut connected to the yolk sac in mammals?

A

o A segment of the yolk sac is incorporated into the embryo to form the primitive gut.
o Temporarily, the middle part of this gut stays connected to the yolk sac through the vitelline duct or yolk stalk.

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11
Q

How do accessory digestive organs form?

A

Accessory organs like the liver and pancreas develop from outpouchings of the primitive gut tube, influenced by molecular signals.

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12
Q

Describe intestinal formation in mammals.

A

The intestines experience physiological umbilical herniation, temporarily protruding into the umbilical cord before retracting back into the abdominal cavity.

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13
Q

How does the mouth form in mammals?

A

o After neurulation, the anterior ectoderm invaginates to form the stomodeum or primary oral cavity.
o The stomodeum contacts the expanding endoderm of the pharynx, initially separated by the buccopharyngeal membrane, which soon ruptures to connect the oral cavity to the pharynx.

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14
Q

What is the role of the cecum in reptiles and other amniotes?

A

Fully developed, plays a crucial role in absorbing water and salts.

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15
Q

What are the major evolutionary changes in the digestive system of amphibians?

A

o Salivary Glands: Evolved to moisturize food, adapting to terrestrial feeding.
o Tongue: Became muscular and motile, actively moving food within the mouth.
o Esophagus: Lengthened to facilitate the movement of food from the mouth to the stomach.
o Intestine: Lost its spiral fold, adapting to different dietary needs.
o Cecum: Developed at the junction of the small and large intestines, aiding in fermentation and digestion.

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16
Q

What are the major digestive system features in mammals?

A

o Mouth Structure: Features prominent, highly motile lips and muscular cheeks for food manipulation.
o Palate: Possesses a well-developed secondary palate with transverse palatal ridges, enhancing food processing capabilities.

17
Q

What are the functions of the tongue?

A

o Primary Functions: Food manipulation and taste perception.
o Specialized Uses: In felines, equipped with horny papillae for meat stripping and grooming; in humans, instrumental in speech production.

18
Q

What are the salivary glands in mammals and their functions?

A

o Number and Types: Four main types—parotid, mandibular (submandibular in humans), sublingual, and zygomatic (absent in humans).
o Main Enzyme and Function: Amylase, crucial for starch breakdown.
o Special Fact About Bat Saliva: Contains draculin, a glycoprotein that acts as an anticoagulant.

19
Q

Describe the structure and variation of the small intestine among animals.

A

o Structure: Elongated and folded to maximize the absorptive surface area.
o Variation Among Animals: Herbivores generally have longer small intestines to efficiently digest plant material.

20
Q

What are the functions of the large intestine?

A

o Relative Length: Shorter than the small intestine but still relatively long.
o Functions: Water absorption, waste storage, and in some small herbivores like rodents and rabbits, houses a large cecum for breaking down crude plant material.

21
Q

What is homodonty and heterodonty in teeth variability?

A

o Homodonty: All teeth are similar, a trait observed in sharks.
o Heterodonty: Teeth differ in shape and function, typical in mammals, including humans.

22
Q

What is the dental formula and what is the human dental formula?

A

o Definition: Describes the number and types of teeth in one half of the mouth for a specific species.
o Human Dental Formula:
 Upper Jaw: 2 Incisors, 1 Canine, 2 Premolars, 3 Molars
 Lower Jaw: 2 Incisors, 1 Canine, 2 Premolars, 3 Molars

22
Q

What causes a congenital umbilical hernia?

A

This condition arises from the incomplete closure of the umbilical ring fascia, allowing intraabdominal contents to protrude. It is notably more common in children of African descent.

23
Q

What is odontogenesis in tooth development?

A

Odontogenesis involves interactions between the oral epithelium and neural crest-derived mesenchyme.

24
Q

How does the oral epithelium contribute to tooth development?

A

The oral epithelium thickens into an arc-shaped dental lamina, with denser areas known as dental placodes forming along it.

25
Q

What is the process of tooth bud formation in odontogenesis?

A

Dental placodes invaginate to create tooth buds, which then form caps and eventually the bell-shaped enamel organ.

26
Q

What forms the dental papilla in tooth development?

A

Beneath the enamel organ, the mesenchyme forms the dental papilla, which will differentiate into the dentin and pulp, while the surrounding mesenchyme will form the cementum.