6.3 Flashcards
Agglutination happens when one persons blood is mixed with ______.
plasma of another person
Define Agglutinate
When cells clump together
The surface of each red blood cell has:
A number of molecules that have antigenic properties
In the plasma, each antibody molecule has
two combining sites for antigens
In a positive agglutination test,
the red blood cells clump together because they are combined through anti-body bridges.
The Rh factor is one of the
Antigens on the surface of the red blood cells
Rh factor is present on the red blood cell membranes on approx.
85% of US citizens
The presence of Rh factor on red blood cells makes the person
An Rh positive phenotype
Rh factor is an inherited as a dominant trait and is produced by both the ______ (RR) genotype and the ______ (Rr) genotype.
Homozygous
Heterozygous
Those who are Rh negative
Do not have the Rh favor on their red blood cells. They have the homozygous recessive genotype
The development of immunological competence dose not occur untill
Shortly after birth
Hemolytic disease of the new born is also called
Erythroblastosis fetalis
Erythroblastosis fetalis is when
An Rh negative mother produces antibodies capable of destroying the red blood cells of SUBSEQUENT Rh positive fetuses.
This happens to the second Rh positive fetus.
How can erythroblastosis fetalis be prevented?
By the administration of exogenous Rh antibodies known as Rho(D) immune globulin within 72 hours of delivery
What does Rho(D) immune globulin do specifically?
It prevents the Rh positive red blood cells that have entered the maternal circulation from stimulating an immune response in the mother.
