6.2.4 - Carbon-Carbon Bond Formation

Question 1

What type of mechanism is
involved in the reaction between
haloalkanes and cyanide ions?

Answer 1

Nucleophilic substitution

Question 2

What type of reaction is involved in
the reaction between carbonyl
compounds and cyanide ions?

Answer 2

Nucleophilic addition

Question 3

How can you form a
carboxylic acid from a
nitrile?

Answer 3

Acid hydrolysis

Question 4

How can you form a
carboxylic acid from a
nitrile?

Answer 4

Acid hydrolysis

Question 5

What type of catalyst is
used for a Friedel-Crafts
reaction?

Answer 5

A halogen carrier (e.g. AlCl3
)

Question 6

Write an equation to form an
electrophile that could be used
to acylate benzene, starting
with AlCl3 and RCOCl

Answer 6

AlCl3
+ RCOCl → AlCl4
-
+ RCO+
(+ on C)
RCO+
can attack benzene

Question 7

How could you use a
Friedel-Crafts mechanism to
add a methyl group to a
benzene ring?

Answer 7

Use a halogenoalkane and AlCl3
to
create an electrophile that can attack
benzene