6.23.16 Block 2 Flashcards

1
Q

complex regional pain synd: ssx

A
  • continued pain (out of proportion to injury)
  • allodynia
  • jt stiff
  • localized edema
  • increased hair growth
  • vasospasm
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2
Q

differentiate: complex regional pain synd type 1 vs 2

A

1: no evidence of nerve damage
2: presence of defined nerve injury

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3
Q

narcolepsy: tx

A

CNS stimulants: modafinil, methylphenidate

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4
Q

SCC of skin: precursor lesion

A

actinic keratoses

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5
Q

actinic keratoses: appearance

A

rough, erythematous, scaly macule/papule

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6
Q

actinic keratoses: RF

A

chronic sun exposure

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7
Q

sup orbital fissure: structs

A
  • CN III, IV, V1, VI

- sympathetics to face

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8
Q

foramen rotundum: structs

A

CN V2

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9
Q

foramen spinosum: structs

A

middle meningeal A

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10
Q

internal auditory meatus: structs

A

CN VII, VIII

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11
Q

jugular foramen: structs

A

CN IX, X, XI

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12
Q

ASA toxicity: ssx

A
  • GI distress
  • tinnitis
  • hyperthermia
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13
Q

what is: Fitz-Hugh-Curtis synd

A

comp of PID: liver capsule inflamm –> adhesions

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14
Q

resistant depression: adjunctive tx

A

lithium

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15
Q

how does vagal stimulation act on gastric parietal cells (on a molecular level)?

A

vagal stim –> release ACh –> activate M3 receptors –> Gq –> phospholipase C

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16
Q

vitelline artery: derivatives

A

SMA

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17
Q

SMA synd: pathophys

A

abd trauma, scoliosis surg, peritoneal adhesion –> shift angle bw abd aorta & SMA –> compress duodenum

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18
Q

what is: anisocytosis

A

variety in RBC size

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19
Q

what anemia presents with increased RDW?

A

iron def

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20
Q

iron def anemia: #1 cause

A

menorrhagia

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21
Q

iron def anemia: lab findings

A
  • low MCV
  • low iron
  • high RDW
  • high TIBC
  • low ferritin
22
Q

Parkinson’s dz: histology hallmark

A

Lewy body: eosinophilic inclusions of a-synuclein

23
Q

anosmia, color blind, no/delayed puberty: dx?

A

Kallman synd

24
Q

Kallman synd: pathophys

A

hypo –> decrease syn of GnRH

25
Q

Kallman synd: ssx

A
  • anosmia
  • color blind
  • no/delayed puberty
26
Q

CASE: young M –> recurrent infect, eczema, low IgM, high IgA –> dx?

A

Wiskott-Aldrich synd

27
Q

AIDS pt –> TB ssx –> what org?

A

mycobact avium intracellulare complex

28
Q

mycobact avium intracellulare complex: at what CD4 count?

A
29
Q

high homogentisate –> dx?

A

alkaptonuria

30
Q

alkaptonuria: enzyme?

A

homogentisate oxidase

31
Q

dermatitis herpetiformis: assoc dz

A

celiac dz

32
Q

CASE: obese, amenorrhea, hirsutism –> dx?

A

PCOS

33
Q

PCOS: hormone levels

A

hyperandrogenic state: high LH, testosterone, estrogen

34
Q

PCOS: what cause amenorrhea?

A

high LH –> anovulation

35
Q

what is: acute dystonia

A

invol contract major muscle grps –> torticollis, oculogyric crisis

36
Q

what is: oculogyric crisis

A

dystonic reaction to certain drugs or medical conditions characterized by a prolonged involuntary upward deviation of the eyes

37
Q

muscle contraction: role of Ca2+

A

Ca2+ bind troponin –> troponin conformation change –> tropomysin mv –> expose myosin binding sites on actin

38
Q

Ehlers-Danlos synd: def

A

collagen III & V

39
Q

hypermobile jt, elastic skin, easy & freq bruise –> dx?

A

Ehlers-Danlos

40
Q

blue sclera –> dx?

A

osteogenesis imperfecta

41
Q

osteogenesis imperfecta: def

A

collagen I

42
Q

compress ant spinal artery –> leads to?

A

ant cord synd

43
Q

ant cord synd: pathophys

A

ischemia to ant 2/3 of spinal cord

44
Q

ant cord synd: effect

A
  • loss: bilat –> motor, pain/temp

- intact: pinpoint, vibration

45
Q

preg –> UTI –> tx?

A

amoxicillin

46
Q

4th & 5th fingers flexed –> can’t extend –> dx?

A

Dupuytren’s contracture

47
Q

REM sleep: hormones involved

A

Ach: initiate
NE: reduce

48
Q

anabolic steroid: SE

A
  • gynecomastia
  • decrease testicular size
  • liver damage
49
Q

pernicious anemia: assoc dz

A

chronic gastritis

50
Q

vitB12 def: histology

A

megaloblastic anemia w hypersegmented neutrophils

51
Q

differentiate: vitB12 def vs folic acid def

A

vitB12 def: increase methylmalonic acid –> neuro ssx