6.2.2 Virus Replication

Question 1

Outline the general virus replication cycle.

Answer 1

1. Attachment
2. Entry
3. Uncoating
4. Gene transcription and translation, production of viral proteins
5. Assembly
6. Release

Question 2

How do viruses attach to the host cell?

Answer 2

bind to a receptor (cellular protein of glycan) on cell surface

Question 3

What is viral tropism?

Answer 3

Ability of a particular virus to infect a particular cell, tissue or host species

Question 4

What are the two method of viral entry?

Answer 4

Endocytosis - viral release via pH change or fusion of viral envelope

Non-endocytosis - virus fuses directly with plasma membrane

Question 5

What is viral uncoating?

Answer 5

release of nucleic acid from viral capsid

very variable