6.1.3 Manipulating Genomes, Applications + Humans Flashcards
Intron
Part of DNA that does not code for a specific amino acid
Gene
A section of genetic code that codes for an amino acid
Locus
Position on a chromosome where a particular allele is found
Human Genome Project (HGP)?
Sequence all 3billion base pairs of human DNA; identify all genes; faster sequencing methods
… of your DNA codes for an amino acid
2%
Comparisons within + between species (app)
Same genes but different alleles; SNPs; can be used to determine parentage, ancestry tests;working genes conserved between species
SNPs?
Single nucleotide polymorphism; random mutations in base sequence that result in differences in alleles
Determine evolutionary relationship (app)
All organisms share a common ancestor, genes can tell us closeness of relationships; bones + teeth of extinct animals can be sequences; species that evolve from one another are genetically similar
Predicting amino acid sequences (app)
Using sequences genomes to predict amino acid sequences + primary protein structure; cytochrome C is an important protein involved in respiration that exists in most organisms; amino acid sequence in the CC can be used to predict the shape, and so how closely related organisms are
Synthetic biology (app)
Ability to sequence the genome of organisms and understand how each sequence is translated into DNA; genetic engineering, altering genetic makeup; use of bio systems in industry; synthesis of new genes to replace faulty ones; synthesis new organisms; synthetic expansion of the genetic code