6 - Molecular basis of Ag recognition Flashcards
1
Q
activated APCs express high levels of these co-stimulatory molecules
A
B7 (B7-1 & B7-2)
or CD80 & CD86
2
Q
Costimulation involves this protein on T cells
A
CD28
3
Q
TCR binding to MHC class II without any co-stimulation leads to
A
anergy of T cell
4
Q
TCR binding to MHC class II with co-stimulation only leads to
A
NO EFFECT on T cell
5
Q
LFA-1 is present on
A
CD4+ T cell
6
Q
ICAM is present on
A
MHC Class II expressing APC
7
Q
specific marker of B cells
coreceptor for BCR
A
CD19
8
Q
specific marker of activated B cells
A
CD20
9
Q
pan B cell markers
A
CD19, CD20, CD22, CD79a, CD79b, FMC7
