6. Fertilization & Gastrulation Flashcards
What are the clinical features of an Hydatidiform Mole? (4)
- Vaginal bleeding
- Pelvic pressure or pain
- Enlarged uterus
- Hyperemesis gravidarum
What is a Choriocarcinoma?
- Malignant tumor which develops from
hydatidiform mole
What is a Hydatidiform Mole?
Abnormal trophoblastic proliferation; excessive amounts of hCG produced
Complete mole results from:
• Fertilization of an empty oocyte, followed by
duplication of the sperm
• Or from fertilization of an empty oocyte by two
sperm
Partial mole results from fertilization of a normal oocyte by two sperm
Passage of sperm through the corona radiata requires which enzyme?
Hyaluronidase
Where does fertilization take place?
Ampulla of the uterine tube
Which two layers must be passed through in the human ovum in order for fertilization to take place?
Corona Radiata and Zona Pellucida
Describe the morula
12-32 cell stage with a zona pellucida around the border
Which layer of the blastocyst transitions to form the placenta?
trophoblast
Blastocyst timing
Day 5-7
Implantation timing
Day 9
Cleavage starts about _____ after fertilization.
30 hours
What happens during week 1?
Formation of the inner cell mast
What happens during week 2?
Formation of the epiblast and the hypoblast
What happens during week 3?
Gastrulation
What 3 primary germ layers form during gastrulation?
Ectoderm, Mesoderm, Endoderm form the trilaminar disc
