6. eukaryotic transcription 1 Flashcards
Where are genes which are not usually expressed found?
heterochromatin
What does the histone code hypothesis propose?
that specific combinations of chemical modifications to histones and DNA of chromatin help determine chromatin configuration and influence transcription
What effect does histone acetylation have?
loosens chromatin structure, promoting initiation of transcription
What effect does histone methylation have?
condenses chromatin
What effect does histone phosphorylation have?
loosens chromatin
Which genes does RNA pol I transcribe? 3
5.8S
28S
18S rRNA genes
Which genes does RNA pol II transcribe? 5
all protein-coding genes snoRNA genes miRNA genes siRNA genes most snRNA genes
Which genes does RNA pol III transcribe? 3
tRNA genes
5S rRNA genes
snRNA genes
Where is the TATA box found on the pol II promotor
-25
What is an example of different Bfs working together?
NFAT and AP-1 - required for productive immune responses