6. Cranium, Meningies, Bld Vessels, Ventricles, CSF, BBB Flashcards
What goes through the superior orbital fissure(4)
III, IV, VI, V1
What goes through optic canal?
CN II
Middle Meningial Artery goes through?
Foramen Spinosum
Path of internal carotid?
carotid foramen–>carotid canal
Path of CN VII
enters internal auditory meatus–>exits via stylomastoid foramen
Path of CN VIII
enters IAM exits external auditory meatus
what exits through jugular foramen?
IX, X, XI
why is XI weird?
spinal branches go in through foramen magnum, join the cranial branches and exit jugular foramen
CN XII exits through
hypoglossal canal
What creates the ant, middle and post cranial fossa?
sphenoid bone ant and petrous bone posterior
3 meningial layers
pia
arachnoid
dura
what separates R and L cerebral hemispheres?
falx cerebri and tentorium cerebelli
2 potential spaces
epidural(arterial bleed) and subdural(venous)
true space
subarachnoid(rupture of large blood vessels)
Epineurium is from ____? Perineurium?
Dura; Arachnoid
Dural Membrane surrounding spinal cord is ____ layer(s)?
1
External Carotid supplies ____, ____, _____
face, scalp, meningies
R and L vertebral branch off ________ and enter vertebral foramen at ___, entering caldaria via ____ and eventually join at pontomedullary jcn forming ______
Subclavian, C6, Foramen Magnum, Basilar Artery
Why is a certain branch of the external carotid very significant?
Middle meningeal can be ruptured with head trauma–>epidural bleed
Circle of Willis
2 vertebral aa give off PICA then form basilar
Basilar gives AICA, pontine branches and superior cerebellar and finally posterior cerebral
Posterior cerebral communicates with interior carotid via posterior communicating
Internal Carotid gives anterior cerebrals which communicate via anterior communicating
Name Venous Sinuses of Brain (6)
Superior Sagittal Inferior Sagittal Straight Sinus Transverse Sinus Cavernous Sinus Great Cerebral Vein(of Galen)
Organization of ventricles in brain?
2 lateral–>interventricular foramen of Monro–>Third Ventricle–>Cerebral Aqueduct(Sylvius)–>Fourth Ventricle
CSF (20ml/hr) created in ____? Reabsorbed in ___?
Choroid Plexus; Arachnoid Granulations
Blockage of interventricular foramen or aqueduct?
Blockage of Arachnoid Granulations?
Obstructive Hydrocephalus-buildup of intraventricular CSF
Non-Obstructive Hydrocephalus
BBB made up of 3 things (via DIT)!!
Tight Junctions, Basement Membrane, Astrocyte foot processes
Structure of Choroid Plexus?
outpouching of capillary and pia into ventricular space, lined by ependymal cells(normal fenestrations)
What are circumventricular organs? examples?
organs that monitor and regulate fluctuations in blood chemistry and lack a blood brain barrier;
-Organum Vasculosum and Neurohypophysis
Octanol/Water Coefficient significance
the more lipid soluble a drug, the easier it gets into the CNS and the faster it leaves; quick in quick out
