6. congenital malformations Flashcards
1
Q
what does a raised nuchal translucency indicate?
A
fluid under the skin of the back of the fetal neck.
raised = high chance of Down’s syndrome (and other chromosomal and heart defects)
2
Q
when is the nuchal translucency test done
A
12/40
aka 12 weeks
3
Q
what are indications of downs syndrome in tests done in the first trimester
A
- maternal serum markers: PAPP-A, free beta-hCG
- fetal marker: raised nuchal thickness
4
Q
what are indications of downs syndrome in tests done in the second trimester
A
maternal serum markers:
- AFP
- E3
- hCG
- inhibin A