6 Cell Membrane Transport - Part 1 Flashcards
Which of the following is not a role of biological
membranes?
A. Like enzymes, it speeds up the transport of
large molecular weight solutes along the
semi- permeable membrane
B. It participates in the proper maintenance of
ionic charges within cells and their
surroundings
C. It prevents enzymes from acting in areas
where they may cause cell lysis and
degradation
D. It defines boundaries inside the cell itself
A. Like enzymes, it speeds up the transport of large
molecular weight solutes along the semi-permeable
membrane
Which cation is more abundant intracellularly
compared to the extracellular compartment?
A. Sodium
B. Magnesium
C. Calcium
D. Bicarbonate
B. Magnesium
What is the structure that most closely resembles a
membrane-bound vesicle?
A. Micelle
B. Soap bubble
C. Liposome
D. Phagosome
C. Liposome
In general, what is the relationship of temperature with
membrane fluidity?
A. As temperature increases, membrane fluidity
increases
B. As temperature increases, membrane fluidity
decreases
C. As temperature decreases, membrane fluidity
increases
D. There is generally no effect of temperature on
membrane fluidity because both are
independent of each other
A. As temperature increases, membrane fluidity
increases
In general, what is the relationship of cholesterol with
membrane fluidity?
A. Below melting temperature, membrane
fluidity increases with an increase in
cholesterol
B. Above melting temperature, an increase in
cholesterol limits fluidity
C. Both A and B are correct
D. Both A and B are incorrect
C. Both A and B are correct
Biological Membranes are said to be asymmetric
because of the unequal distribution of phospholipids in
the inner and outer leaflet of membranes. Which of the following
phospholipids is most commonly seen in the
inner leaflet of membranes?
A. Phosphatidylethanolamine
B. Phosphatidic acid
C. Phosphatidylcholine
D. Sphingomyelin
A. Phosphatidylethanolamine
Cellular degradation analysis shows a high
preponderance of the enzyme ATP synthase. This
most probably signifies:
A. An extensive plasma membrane network in
the cell
B. A large amount of glucose-6-phosphatases
C. A cell with plenty of mitochondria
D. A very active Golgi Complex
C. A cell with plenty of mitochondria
In the sodium-potassium ATPase pump,
phosphorylation of the Aspartic acid residue of the
alpha subunit protein results in:
A. The attachment of sodium ions to the alpha
subunit
B. An increase in the affinity of potassium ions to
the alpha subunit
C. The cleavage of aspartic acid from the
Na-K-ATPase transport protein
B. An increase in the affinity of potassium ions to the
alpha subunit
The drug digoxin, a digitalis derivative, inhibits the
sodium-potassium-ATPase pump in myocardial cells.
This results in:
A. An increased synthesis of ATP in the cell
B. An increase in the intracellular calcium ion
concentration
C. Depolarization of the cardiac cell
D. Vasodilation
B. An increase in the intracellular calcium ion
concentration
Which of the following is not a membrane lipid?
A. Cholesterol
B. Triacylglycerol
C. Phosphatidylcholine
D. Sphingomyelin
B. Triacylglycerol
Which of the following neurotransmitters activate
muscle fibers in the neuromuscular junction?
A. Acetylcholine
B. Nicotine
C. Dopamine
D. Serotonin
A. Acetylcholine
Which of the following has the highest membrane
permeability coefficient?
A. Water
B. Sodium
C. Glucose
D. Cortisol
B. Cortisol
Which of the following is equally distributed (same
concentration) between the inner and outer leaflet of
the lipid bilayer?
A. Phosphatidylcholine
B. Phosphatidylethanolamine
C. Sphingomyelin
D. None of the above
D. None of the above
Why is it more common to see lateral flip flops in cell
membranes compared to transverse flip flops?
A. Lateral flip flops happen more spontaneously
compared to transverse flip flops
B. Transverse flip flops tend to cause cell death
C. Transverse flip flops are energy-requiring
changes
D. Lateral flip flops have to happen multiple
times first before a transverse flip flop occurs
B. Transverse flip flops tend to cause cell death
All of the following are amphipathic molecules,
EXCEPT:
A. Peripheral membrane proteins
B. Integral membrane proteins
C. Free cholesterol
D. Glycosphingolipids
A. Peripheral membrane proteins
Which of the following is a characteristic of a ligand-gated ion channel?
A. It functions by hydrolyzing ATP to transport ions against their gradient.
B. It remains permanently open once activated by a ligand.
C. It opens or closes in response to the binding of a specific molecule.
D. It allows the passage of nonpolar molecules across the membrane.
C. It opens or closes in response to the binding of a specific molecule.
What is the primary function of G-protein-coupled receptors (GPCRs)?
A. Directly phosphorylating target proteins in the cell.
B. Serving as ion channels for specific cations and anions.
C. Transmitting signals from extracellular ligands to intracellular G-proteins.
D. Degrading ligands after signal transduction.
C. Transmitting signals from extracellular ligands to intracellular G-proteins.
Which of the following does not participate in the signal transduction mechanism of receptor tyrosine kinases (RTKs)?
A. Autophosphorylation of the receptor.
B. Activation of downstream intracellular signaling proteins.
C. Direct binding to and activation of nuclear DNA.
D. Dimerization of the receptor upon ligand binding.
C. Direct binding to and activation of nuclear DNA.
In facilitated diffusion, which of the following is true?
A. Molecules move against their concentration gradient with the help of carrier proteins.
B. Energy in the form of ATP is required for the transport process.
C. The transport process is saturable, meaning it can reach a maximum rate.
D. It involves the direct interaction of small nonpolar molecules with the lipid bilayer.
C. The transport process is saturable, meaning it can reach a maximum rate.
Which of the following best describes the sodium-potassium pump (Na+/K+ ATPase)?
A. It transports three sodium ions into the cell and two potassium ions out of the cell.
B. It is a passive transport mechanism that does not require energy.
C. It plays a critical role in maintaining the cell’s membrane potential.
D. It allows for the passive diffusion of sodium and potassium ions across the membrane.
C. It plays a critical role in maintaining the cell’s membrane potential.
Which of the following statements about active transport is incorrect?
A. Active transport can move molecules from areas of low concentration to high concentration.
B. It requires energy, often in the form of ATP, to function.
C. It is always coupled with the transport of another molecule in the same direction.
D. It often involves carrier proteins that change shape during the transport process.
C. It is always coupled with the transport of another molecule in the same direction.
Which of the following types of transport does not require energy input?
A. Active transport
B. Facilitated diffusion
C. Primary active transport
D. Cotransport
B. Facilitated diffusion
What is the primary role of cholesterol in the plasma membrane?
A. Increasing membrane permeability to ions
B. Stabilizing membrane fluidity across temperature changes
C. Acting as a receptor for extracellular signals
D. Facilitating the transport of glucose into the cell
B. Stabilizing membrane fluidity across temperature changes
Which ion is most commonly pumped out of the cell by the Na+/K+ ATPase?
A. Potassium
B. Sodium
C. Calcium
D. Chloride
B. Sodium