6 - Cell division Flashcards
what is the cell cycle?
- the process that all body cells in multicellular organisms use to grow and divide.
- series of stages for a cell to divide into 2 genetically identical daughter cells.
- starts with one cell already produced by cell division and ends with 2 genetically identical daughter cells being produced.
what are the functions of the cell cycle?
- growth of tissue/organism.
- replacement of worn out/damaged cells.
- to repair damaged tissues.
- asexual reproduction in plants, animals, fungi
end products of cell cycle is?
2 genetically identical daughter cells.
stages of cell cycle:
- interphase: G1 phase (G1 checkpoint) S phase G2 phase (G2 checkpoint) - mitotic phase: mitosis cytokinesis
G1 phase?
- first growth phase
- synthesis of proteins
- organelles replicate
- cell increases in size
S phase?
- synthesis phase
- each chromosome is replicated in the nucleus
G2 phase?
- second growth phase
- cell continues to grow in size.
- energy stores increase
- duplicated DNA checked for errors
- proteins needed for cell division are needed.
mitosis?
the nucleus divides
cytokinesis?
the cytoplasm divides and two cells are produced.
How is the cell regulated?
- by checkpoints.
they monitor and verify whether the processes at each phase of the cell cycle have been accurately completed before moving onto the next.
G1 checkpoint
checks for:
- cell size
- nutrients
- growth factors
- DNA damage
G2 checkpoint
checks for
- cell size
- DNA replication
- DNA damage
spindle assembly checkpoint
checks for:
- chromosome attachment to spindle.
G0
- phase when cell leaves the cycle temporarily or permanently
- differentiation
- DNA damage
- as you age, no. of cells that enter G0 increase.
what are the stages of mitosis?
- prophase
- metaphase
- anaphase
- telophase
PMAT
Prophase
- chromosomes condense and thicken (become visible)
- each chromosome consists of 2 sister chromatids joined at centromere.
- two centrioles move to opposite poles of cell.
- spindle fibres attach to specific areas on centromeres and start to move chromosomes to equator of the cell.
- nuclear envelope disappears.
Metaphase
- individual chromosomes are moved by spindle fibres to align at equator of cell.
- chromosomes are attached to the spindle fibres by the centromere.
Anaphase
- centromeres holding the pairs of chromatids in each chromosome divide.
- spindle fibres contract
- each chromatid is pulled by their centromere to opposite sides of the cell.
Telophase
- chromatids reach opposite sides of the cell
- chromatids uncoil and become long and thin again.
- they are now called chromosomes (each chromosome now consists of one chromatid).
- spindle fibres disappear
- nuclear envelope reforms and enclose around the chromosomes at each pole.
Cytokinesis
- cytoplasm divides.
- in animal cells, a cleavage furrow forms to divide the cell surface membrane.
- forms 2 genetically identical daughter cells.
- begins in anaphase, ends in telophase.
- separate process to mitosis.
no of chromatids in the stages of cell division?
- one chromatid per chromosome before replication.
- two chromatids per chromosome after replication
- one chromatid per chromosome after mitotic division.
cytokinesis in plant cells?
- cell plate forms, 2 genetically identical daughter cells are formed.
what are homologous chromosomes?
homologous pair of chromosomes contain one maternal and one paternal chromatid.
same genes but different alleles.
What is meiosis?
the process by which sex cells (gametes) are made in the reproductive organs.
Importance of meiosis?
- gametes are produced
- promotes genetic variation in offspring.
- promotes genetic variation and allows for natural selection to take place.
How does genetic variation occur in meiosis?
- crossing over in prophase 1
- independent assortment in metaphase 1
why are gametes haploid?
- they only have one copy of each chromosome
- 23 chromosomes
- haploid
why are body cells diploid?
- they have two of each chromosome
- 46 chromosomes (23 pairs)
- diploid.