6/16- Neuro-oncology III Flashcards
Meningiomas are typically what grade?
Grade 1
- Well-circumscribed
- Surgically resectable (although over convexity is much easier than in cavernous sinus…)
They can progress to a higher grade (there is such a thing as a malignant meningioma), but they’re rare
What is this?
Meningioma
What is this?
Meningioma
What kind of cells form meningiomas? Where are they located?
Meningoethelial cells
- Located in dura and arachnoid caps?
What is this?
Meningioma???
Where can a Schwannoma occur? Common?
Anywhere there are Schwann cells
- Peripheral nerves
- Any cranial nerves
- Very common = CN 8 (cerebro-pontine angle/ponto-medullary junction)
What is this?
Meningoethelial cells
What is this?
Meningioma of the lateral convexity
What is this?
Meningioma
What is this? Origin?
Meningioma of the optic nerve
- Arises from dural sheath of the nerve
Symptoms of CP angle Schwannoma
(auditory neuroma - bad terminology)?
- Unilateral hearing loss
- Tinnitus possible
- Nystagmus and vertigo if vestibular n. involved
- Can compress adjacent nerves (e.g. 5 and 7) if it enlarges
Compare these two tumors of the optic nerve. What are they?
L = Meningioma
R = Pilocytic __?
What is this?
Meningioma histopathology
(Little Orphan Annie cells??)
What is this?
Meningioma histopathology
What is this?
Meningioma histopathology
- Hurricane/tropical storm cells
- Psammoma bodies
- Little Orphan Annie cells??
What can be used to confirm that something is a meningioma?
- Epithelial membrane antigen