5.2 Natural Selection Flashcards
Who proposed the theory of natural selection?
The theory of natural selection was posited by Charles Darwin (and also Alfred Wallace) who described it as ‘survival of the fittest’
What species is most likely to survive, in terms of natural selection?
According to this theory, it is not necessarily the strongest or most intelligent that survives, but the ones most responsive to change
In response to what conditions does natural selection occur (5)?
inherited variation
competition
selection
adaptations
evolution
How does natural selection occur in relation to inherited variation?
Inherited Variation – There is genetic variation within a population which can be inherited
How does natural selection occur in relation to competition?
Competition – There is a struggle for survival (species tend to produce more offspring than the environment can support)
How does natural selection occur in relation to selection?
Selection – Environmental pressures lead to differential reproduction within a population
How does natural selection occur in relation to adaptations?
Adaptations – Individuals with beneficial traits will be more likely to survive and pass these traits on to their offspring
How does natural selection occur in relation to evolution?
Evolution – Over time, there is a change in allele frequency within the population gene pool
What is the summary of natural selection (mnemonic)
Inherited variation exists within the population
Competition results from an overproduction of offspring
Environmental pressures lead to differential reproduction
Adaptations which benefit survival are selected for
Genotype frequency changes across generations
Evolution occurs within the population
Mnemonic: ICE AGE
What does natural selection require?
Natural selection requires variation among members of a species in order to differentiate survival (variation needed for selection)
In what forms can variation arise?
This variation can manifest as either discontinous (distinct classes) or continuous (range across a characteristic spectrum)
What are the 3 main mechanisms in which variation may occur in an individual?
mutations
meiosis
sexual reproduction
How do mutations lead to variation?
Mutations – Changing the genetic composition of gametes (germline mutation) leads to changed characteristics in offspring
How does meiosis lead to variation?
Meiosis – Via either crossing over (prophase I) or independent assortment (metaphase I)
How does sexual reproduction lead to variation?
Sexual reproduction – The combination of genetic material from two distinct sources creates new gene combinations in offspring
What is a gene mutation?
A gene mutation is a change in the nucleotide sequence of a section of DNA coding for a specific trait
What is formed by mutations?
New alleles are formed by mutation
What 3 types of gene mutations are there?
Gene mutations can be beneficial, detrimental or neutral
What are beneficial mutations?
Beneficial mutations change the gene sequence (missense mutations) to create new variations of a trait
What are detrimental mutations?
Detrimental mutations truncate the gene sequence (nonsense mutations) to abrogate the normal function of a trait
What are neutral mutations?
Neutral mutations have no effect on the functioning of the specific feature (silent mutations)
What does crossing over involve? (meiosis)
Crossing over involves the exchange of segments of DNA between homologous chromosomes during prophase I
Where does the exchange of genetic material occur in meisosis?
The exchange of genetic material occurs between non-sister chromatids at points called chiasmata
What does crossing over lead to in terms of the 4 chromatids? meiosis
As a consequence of this recombination, all four chromatids that comprise the bivalent will be genetically different
What will the chromatids consist of in meiosis?
Chromatids that consist of a combination of DNA derived from both homologous chromosomes are called recombinants
What will offspring with recombinant chromosomes have?
Offspring with recombinant chromosomes will have unique gene combinations that are not present in either parent
What is random in meiosis?
When homologous chromosomes line up in metaphase I, their orientation towards the opposing poles is random
What is independent assortment?
The orientation of each bivalent occurs independently, meaning different combinations of maternal / paternal chromosomes can be inherited when bivalents separate in anaphase I
What is the total number of combinations that can occur in gametes?
The total number of combinations that can occur in gametes is 2n – where n = haploid number of chromosomes
How many different gametes can humans produce?
Humans have 46 chromosomes (n = 23) and thus can produce 8,388,608 different gametes (223) by random orientation
How many different gametes can humans produce WITH crossing over?
If crossing over also occurs, the number of different gamete combinations becomes immeasurable
What does the fusion of two haploid gametes result in?
The fusion of two haploid gametes results in the formation of a diploid zygote
What can a zygote do to form an embryo?
This zygote can then divide by mitosis and differentiate to form a developing embryo
How does random fertilisation occur?
As meiosis results in genetically distinct gametes, random fertilisation by egg and sperm will always generate different zygotes
Due to random fertilisation what does offspring show?
This means that individual offspring will typically show variation despite shared parentage