5. T Cells Flashcards
1
Q
Tacrolimus?
A
Potent immunosuppressive drug that prevents T cell expression
2
Q
What will T cells produce once they’ve been activated?
A
IL-2, which is a T cell growth factor
3
Q
DiGeorge syndrome?
A
Deletion on chromosome 22, causing T cell deficiency.
Clinical signs: developmental/neuromuscular/cardiac defects, hypothyroidism, immune dysfunction
4
Q
SCID
A
Mutation in IL-2 receptor + cytokine receptors affected
Particular mutation for encoding common gamma chain, which is part of the IL-2 receptor
