5. Proteins Flashcards
Topic - Proteins
@ Hetro/homo polymer
@ Linear chain of
@ di-peptide bond formed when _
@
Proteins are ____ (homo/hetero) polymers of amino acids.
Hetropolymers (made up of diff monomeric units)
Proteins are polypeptides. i.e., linear chains of amino acids linked by ______ bonds.
peptide bonds
*Peptide bond of Di-peptide Amino Acid is formed when:
(–COOH) group of one amino acid reacts with the (–NH2) group of the next amino acid by releasing one water molecule (dehydration)
Topic - Functions of Proteins
@ Responsible for _
@ Transport nutrients
@ Intercellular ground substance
@ Antibodies to fight
@ Act as Receptor/Hormone/Enzyme/Pigment
@ Most abundant protein
Proteins are responsible for growth and tissue repair.
T/F
True
Proteins transport nutrients across cell membranes.
Example.
GLUT-4 enables glucose transport into the cell
Proteins act as intercellular ground substances.
Example.
Collagen
Protein acts as antibodies to fight infectious
organisms.
T/F
True
Example when protein acts as:
1. Receptors
2. Hormones
3. Enzymes
4. Pigments
- Receptors of smell, taste, hormones
- Insulin
- Trypsin
- Hemoglobin
Most abundant protein in the animal world:
Collagen
Most abundant protein in the biosphere:
RuBisCO
(Ribulose bisphosphate carboxylase - oxygenase)
*Topic - Primary Structure of Protein
@ Position info
@ _ bonds
@ Left end / Right end
______ structure describes the sequence of amino acids, i.e., the positional information in a protein.
Primary structure
The primary structure has ____ bonds.
Peptide bonds
In the chain of Primary structure:
a. Left end has -
b. Right end has -
a. 1st amino acid
(N-terminal amino acid)
b. Last amino acid
(C-terminal amino acid)
Topic - Secondary Structure of Protein
@ _ bonds
@ folded as _ or _ sheets
@ α / β -helix is ______ bond.
@ Right/left helix
@ Examples
The secondary structure has ____ bonds.
Peptide bond + H bond
The secondary structure, thread, is folded as ____ or ____ sheets.
α-helix or β-pleated sheets
I. α-helix is ______ bond.
II. β-pleated is ______ bond.
I. Intra-molecular H bond
II. Intermolecular H bond.
In the Secondary structure, Proteins have zig-zag and only right-handed helices.
T/F
True
Examples of Secondary Structure:
I. α-helix present in ____.
II. β-helix present in ____.
I. Keratin
II. Fibroin
Topic - Tertiary Structure of Protein
@ _ bonds
@ Hollow _ ball
@ Most stable and necessary for
@ Examples
The tertiary structure has ____ bonds.
Peptide bond + H bond + di-Sulphide bond
In the Tertiary structure, the helical polypeptide chain is further folded like a hollow ______ ball.
woolen globular ball
Tertiary structure gives a 3-d view and is most stable and necessary for many biological activities of proteins.
T/F
True
Examples of Tertiary Structure:
I. Myoglobin
II. All enzymes
Topic - Quaternary Structure Protein
@ Different polypeptide chain
@ Each chain function as _
@ Examples
In ______ structure, proteins have more than one polypeptide chain forming a tertiary structure, and each chain functions as a subunit of protein.
Quaternary structure
Examples of Quaternary structure Protein.
Human Hemoglobin (4 subunits = 2α+2β)