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[OS 217] Oncology > [5] Pediatric Oncology > Flashcards

[5] Pediatric Oncology Flashcards

1
Q

What is the incidence of malignancies occurring in children?

A

1%

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2
Q

Define: Trismus

A

Inability to open mouth

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3
Q

Most common childhood cancer worldwide

A

Acute Lymphoblastic Leukemia

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4
Q

“True” 2nd most common cancer in children

A

Solid Tumor Brain Cancer (Medulloblastoma)

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5
Q

Children with Down Syndrome have an increased risk for developing this kind of cancer

A

Acute Myelogenous Leukemia

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6
Q

Children with Beckwith Wiedemann Syndrome have an increased risk for developing this kind of cancer

A

Hepatoblastoma

Wilm’s Tumor

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7
Q

Red Flag indicator for Leukemia in a CBC

A

Very high lymphocyte count

Very low hemoglobin and platelets

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8
Q

If an ALL spreads to the chest, does this have a better or worse prognosis than if it spread to the abdomen?

A

If has a worse prognosis because it indicates an origin from the Thymus affecting T-cells, aBdominal spread indicates B-cell affectation and better prognosis

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9
Q

Test to differentiate between T and B cell Leukemia

A

Flow Cytometry (X-Ray can be used if funding is an issue, mediastinal node involvement is more likely T-Cell)

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10
Q

ALL Blast Cell Sanctuary Sties

A

Brain

Testicle

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11
Q

A fever of malignancy can be given this drug to check if it is indeed a malignancy

A

Naproxen

If the fever goes away immediately, it is most probably a malignancy

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12
Q

Peak ages of Hodgkin’s Lymphoma

A

1st Peak: Adolescence

2nd Peak: 50-60 y/o

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13
Q

Hodgkin’s Lymphoma is more common in males/females?

A

Males

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14
Q

This cancer is the most frequent cause of intussusception in children >6 years old

A

Non-Hodgkin’s Lymphoma

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15
Q

Usual location of brain tumors in children >8 y/o

A

Supretentorial

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16
Q

Usual location of brain tumors in children

A

Infratentorial

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17
Q

2nd most common solid tumor in children

A

Neuroblastoma

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18
Q

Most common location of a neuroblastoma

A

Abdominal presentation

19
Q

Most common pediatric malignancy of the kidney

A

Wilms’ Tumor

20
Q

Peak Age at Diagnosis of Wilms’ Tumor

A

2-3 Years

21
Q

Why is Thrombocytosis common in Hepatoblastoma Patients?

A

Results from production of cytokine members including TPO (Thrombopoietin), within tumor tissues

22
Q

Most common liver tumor of childhood

A

Hepatoblastoma

23
Q

First sign of Retinoblastoma

A

Leukocoria

24
Q

Classic Radiologic Finding in Langerhans Cell Histiocytosis

A

Lytic Bone Lesion (Face or Base of Skull)

25
Q

A 2-year-old male with macroglossia and RUQ mass

a. Leukemia
b. Hepatoblastoma
c. Non-Hodgkin Lymphoma
d. Neuroblastoma

A

B

26
Q

3 year old female with 2 week history of ataxia and diplopia. Midline cerebellar mass on MRI

a. Leukemia
b. Wilm’s Tumor
c. Medulloblastoma
d. Retinoblastoma

A

C

27
Q

Best treatment option for Acute Leukemia

a. Chemotherapy
b. Surgery
c. Radiation
d. Chemotherapy and Surgery

A

A

28
Q

A patient with Leukocoria, OD, of 4 mos duration, presents to the ophtha clinic. There is a family history of eye tumors, but specific dx unrecalled. This is most likely?

a. Medulloblastoma
b. Astrocytoma
c. Orbital sarcoma
d. Retinoblastoma

A

D

29
Q 
Which of the ff would most likely present as an
asymptomatic abdominal mass?
a. Neuroblastoma
b. Hepatoblastoma
c. Wilms
d. Retinoblastoma
A

C

30
Q

Neuroblastoma occurs

a. Only in the abdomen
b. Anywhere along the sympathetic chain
c. Anywhere along the spinal column

A

B

31
Q

Most common childhood cancer

a. Brain tumors
b. Lung carcinomas
c. Leukemias
d. Retinoblastoma

A

C

32
Q

Most common solid tumor in children

a. Neuroblastoma
b. Hepatoblastoma
c. Brain Tumors
d. Lymphoma

A

C

33
Q

Current survival in ALL in children

a. 80-90%
b. 20-30%

A

A

34
Q

A tumor commonly seen in the first year of life

a. Osteosarcoma
b. Lymhomha
c. Hodgkin’s Lymphoma
d. Hepatoblastoma

A

D

35
Q

Which would most likely present as an asymptomatic abdominal mass?

a. Neuroblastoma
b. Hepatoblastoma
c. Wilms
d. Retinoblastoma

A

C

36
Q

Treatment of medullablastoma involves

a. Surgery only
b. Surgery and chemotherapy
c. Surgery, chemotherapy and radiotherapy
d. Radiotherapy only

A

C

37
Q

Supratentorial brain tumors most often seen in

a. 8 years old

A

B

38
Q

True regarding Wilm’s Tumor

a. Presents as an asymptomatic abdominal mass
b. Common in adolescence
c. Most common hepatic tumor in children

A

A

39
Q

Most common presentation of retinoblastoma

a. Leukocoria
b. Proptosis

A

A

40
Q

Childhood cancer is

a. Mostly untreatable
b. Mostly curable

A

B

41
Q

Childhood cancer is

a. Rare
b. Common
c. Mostly difficult to treat

A

A

42
Q

Early detection

a. Improves cure rate
b. May decrease intensity of therapy
c. Aand B

A

C

43
Q

Pediatric cancer is on the

a. Rise
b. Decline

A

A

[OS 217] Oncology (6 decks)

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