[5] Pediatric Oncology

Question 1

What is the incidence of malignancies occurring in children?

Answer 1

1%

Question 2

Define: Trismus

Answer 2

Inability to open mouth

Question 3

Most common childhood cancer worldwide

Answer 3

Acute Lymphoblastic Leukemia

Question 4

“True” 2nd most common cancer in children

Answer 4

Solid Tumor Brain Cancer (Medulloblastoma)

Question 5

Children with Down Syndrome have an increased risk for developing this kind of cancer

Answer 5

Acute Myelogenous Leukemia

Question 6

Children with Beckwith Wiedemann Syndrome have an increased risk for developing this kind of cancer

Answer 6

Hepatoblastoma

Wilm’s Tumor

Question 7

Red Flag indicator for Leukemia in a CBC

Answer 7

Very high lymphocyte count

Very low hemoglobin and platelets

Question 8

If an ALL spreads to the chest, does this have a better or worse prognosis than if it spread to the abdomen?

Answer 8

If has a worse prognosis because it indicates an origin from the Thymus affecting T-cells, aBdominal spread indicates B-cell affectation and better prognosis

Question 9

Test to differentiate between T and B cell Leukemia

Answer 9

Flow Cytometry (X-Ray can be used if funding is an issue, mediastinal node involvement is more likely T-Cell)

Question 10

ALL Blast Cell Sanctuary Sties

Answer 10

Brain

Testicle

Question 11

A fever of malignancy can be given this drug to check if it is indeed a malignancy

Answer 11

Naproxen

If the fever goes away immediately, it is most probably a malignancy

Question 12

Peak ages of Hodgkin’s Lymphoma

Answer 12

1st Peak: Adolescence

2nd Peak: 50-60 y/o

Question 13

Hodgkin’s Lymphoma is more common in males/females?

Answer 13

Males

Question 14

This cancer is the most frequent cause of intussusception in children >6 years old

Answer 14

Non-Hodgkin’s Lymphoma

Question 15

Usual location of brain tumors in children >8 y/o

Answer 15

Supretentorial

Question 16

Usual location of brain tumors in children

Answer 16

Infratentorial

Question 17

2nd most common solid tumor in children

Answer 17

Neuroblastoma

Question 18

Most common location of a neuroblastoma

Answer 18

Abdominal presentation

Question 19

Most common pediatric malignancy of the kidney

Answer 19

Wilms’ Tumor

Question 20

Peak Age at Diagnosis of Wilms’ Tumor

Answer 20

2-3 Years

Question 21

Why is Thrombocytosis common in Hepatoblastoma Patients?

Answer 21

Results from production of cytokine members including TPO (Thrombopoietin), within tumor tissues

Question 22

Most common liver tumor of childhood

Answer 22

Hepatoblastoma

Question 23

First sign of Retinoblastoma

Answer 23

Leukocoria

Question 24

Classic Radiologic Finding in Langerhans Cell Histiocytosis

Answer 24

Lytic Bone Lesion (Face or Base of Skull)

Question 25

A 2-year-old male with macroglossia and RUQ mass a. Leukemia b. Hepatoblastoma c. Non-Hodgkin Lymphoma d. Neuroblastoma

Answer 25

B

Question 26

3 year old female with 2 week history of ataxia and diplopia. Midline cerebellar mass on MRI a. Leukemia b. Wilm’s Tumor c. Medulloblastoma d. Retinoblastoma

Answer 26

C

Question 27

Best treatment option for Acute Leukemia a. Chemotherapy b. Surgery c. Radiation d. Chemotherapy and Surgery

Answer 27

A

Question 28

A patient with Leukocoria, OD, of 4 mos duration, presents to the ophtha clinic. There is a family history of eye tumors, but specific dx unrecalled. This is most likely? a. Medulloblastoma b. Astrocytoma c. Orbital sarcoma d. Retinoblastoma

Answer 28

D

Question 29

``` Which of the ff would most likely present as an asymptomatic abdominal mass? a. Neuroblastoma b. Hepatoblastoma c. Wilms d. Retinoblastoma ```

Answer 29

C

Question 30

Neuroblastoma occurs a. Only in the abdomen b. Anywhere along the sympathetic chain c. Anywhere along the spinal column

Answer 30

B

Question 31

Most common childhood cancer a. Brain tumors b. Lung carcinomas c. Leukemias d. Retinoblastoma

Answer 31

C

Question 32

Most common solid tumor in children a. Neuroblastoma b. Hepatoblastoma c. Brain Tumors d. Lymphoma

Answer 32

C

Question 33

Current survival in ALL in children a. 80-90% b. 20-30%

Answer 33

A

Question 34

A tumor commonly seen in the first year of life a. Osteosarcoma b. Lymhomha c. Hodgkin’s Lymphoma d. Hepatoblastoma

Answer 34

D

Question 35

Which would most likely present as an asymptomatic abdominal mass? a. Neuroblastoma b. Hepatoblastoma c. Wilms d. Retinoblastoma

Answer 35

C

Question 36

Treatment of medullablastoma involves a. Surgery only b. Surgery and chemotherapy c. Surgery, chemotherapy and radiotherapy d. Radiotherapy only

Answer 36

C

Question 37

Supratentorial brain tumors most often seen in | a. 8 years old

Answer 37

B

Question 38

True regarding Wilm’s Tumor a. Presents as an asymptomatic abdominal mass b. Common in adolescence c. Most common hepatic tumor in children

Answer 38

A

Question 39

Most common presentation of retinoblastoma a. Leukocoria b. Proptosis

Answer 39

A

Question 40

Childhood cancer is a. Mostly untreatable b. Mostly curable

Answer 40

B

Question 41

Childhood cancer is a. Rare b. Common c. Mostly difficult to treat

Answer 41

A

Question 42

Early detection a. Improves cure rate b. May decrease intensity of therapy c. Aand B

Answer 42

C

Question 43

Pediatric cancer is on the a. Rise b. Decline

Answer 43

A