5] Hematologic Flashcards
Hematologic disease are disorders of?
RBC
WBC
Platelet
Coagulation
Disorders of RBCs (3)
Anemia
Polycythemia
Sickle cell anemia
Disorders of WBCs (3)
Leukocytosis
Leukopenia
Leukemia
Platelet disorders (2)
Thrombocytopenia
Thrombocytosis
Coagulation disorder
Hemophilia
Risk factors for hemat disorder
Meds Surgery Hypercoagulable conditions Thromboembolism Others vary
Exertion signs and Sx for hemat
Chest pain Dyspnea Palpitations Weakness Fatigue
5 general signs and Sx categories for hemat
Exertion Skin and fingernail Neuro Stool Infections
Skin and finger signs and Sx for hemat
Observe Pallor Cyanosis Clubbing Bruising/bleeding
Neuro signs and Sx for hemat
Headache Drowsy Syncope Dizzy Polyneuropathy
Define anemia
reduction in oxygen-carrying capacity of blood due to abnormal quality/quantity of RBCs
Hemoglobin level for men
Less than 14 g/100ml
Hemoglobin level for women
Less than 12 g/100ml
Etiology of anemia
Excessive blood loss
Increased destruction of RBCs
Decreased production of RBCs
Is anemia a disease
No
- A symptom of other disorders
- Chronic blood loss
- Dietary deficiency
- Chronic disease (RA, neoplasm, SLE, infection, etc.)
- Complication of chemotherapy
Anemia
Population affected with anemia
Post op b/c of blood loss
Occult
Excessive iron loss through sweat
Female
Signs and sx of anemia (6)
Pallor Fatigue DOE Angina Low diastolic BP CNS changes
Headache, dizziness,
syncope, drowsiness,
depression, slow thought
processes, polyneuropathy
CNS changes for anemia
Additional signs and sx for anemia (4)
Nail bed changes
Pale and warm palms
Conjunctive and oral mucous: maybe pale and yellow
Decreased exercise tolerance
Koionychia
Nail bed changes
Sickle cell disease is what type?
Inherited, autosomal, recessive
What is sickle cell anemia, define
Abnormal form of gB
RBC shape: altered
• Chronic hemolytic anemia
• Vaso-occlusion
Sickle cell anemia
Risk factors for sickle cell
Ancestry - Africa, india, Saudi, Mediterranean
Signs and Sx of sickle cell
Pain: damaged tissue b/c of clots
Low grade fever
Other body systems impacted
Thrombocytopenia
• Platelet count:
Less than 150,000/cc blood
Etiology of thrombocytopenia
Decreased production
Accelerated platelet destruction
Sequestration in the spleen
Complications of thrombo
Neoplasm: leukemia, metastatic
Chemotherapy
Aspirin & NSAID use
Signs and Sx for thrombo
Bleeding: mucosa