5: Coagulation Flashcards
_____ adhere to vessel wall when damage occurs to begin the clotting process.
Platelets adhere to vessel wall when damage occurs to begin the clotting process.
What forms platelets?
Megakaryocytes in the bone marrow.
PT measures which factors?
- 1
- 2
- 5
- 7
- 10
If a patient on heparin has lupus anticoagulant, what is used to monitor heparin therapy?
Factor 10 A levels
PTT measures which factors?
- 1
- 2
- 5
- 8
- 9
- 10
- 11
- 12
T/F Heparin contamination from lines can give falsely elevated PTT.
True
This is used to monitor heparin therapy.
PTT
PT/INR is most sensitive to what clotting factors?
PT: Vitamin K-dependent clotting factors:
- 2
- 7
- 9
- 10
INR: Hereditary factor deficiencies:
- 1
- 5
- 7
- 10
_____ represent fibrin degradation of a blood clot after fibrinolysis.
D-dimer represent fibrin degradation of a blood clot after fibrinolysis.
T/F During primary hemostatis, platelets move from aggregation to adhesion to coagulation.
False. They move from adhesion to aggregation to coagulation.
This is used to monitor coumadin therapy.
PT/INR
Where is fibrinogen synthesized?
Liver
PT/INR evaluates _____ and _____ pathway.
PT/INR evaluates extrinsic and common pathway.
PTT evaluates _____ and _____ pathway.
PTT evaluates intrinsic and common pathway.
Fibrinogen is involved in clot formation during what stage?
Secondary hemostasis
