5. Acute Coronary Syndrome Flashcards
What are the two types of acute coronary syndromes?
Unstable angina and myocardial infarctions
What is the common underlying pathology that they both share?
What are some other causes of ACS?
Plaque rupture, thrombosis and inflammation
Emboli, coronary spasm or vasculitis
How do you differentiate between unstable angina and myocardial infarction?
MI- rise in troponin
Unstable angina- no rise in troponin
What are the two types of myocardial infarctions?
Which is worse and why?
NSTEMI- worse due to the fact the coronary artery is completely blocked
STEMI-
How sensitive of a biochemical marker is troponin?
Very good and can differentiate between skeletal and cardiac muscle injury- GP online
Not specific- gynae surgeon ❓
Best used 10-12 hours after event, can use pre troponin assays if needed- NICE
What are some risk factors that cause MI’s
Age Being a man Family history of IHD smoking Hypertension Diabetes Obesity/sedentary lifestyle
What troponins are most specific to the heart?
Troponins I and T
What (other than MI) can raise troponin levels?
Myocarditis, pericarditis, ventricular strain, discrete tchyarrhythmias
What are the symptoms of an MI?
Acute central chest pain lasting> 20 mins
May come with nausea, sweatiness, dyspnoea, palpitations, distress and anxiety
What is a silent MI?
How does it present?
MI without chest pain, more common in diabetics or the elderly
Syncope Pulmonary odema Epigastric pain Hypotension (post-op) Acute confusion
What tests are done for an MI?
ECG
Cardiac enzymes
Echo
What are the differential diagnosis for an MI?
Stable angina Pericarditis Myocarditis Takotsubo Aortic dissection Oesophageal reflux Pneumothorax, pancreatitis MSk pain
What categorised how acute coronary syndrome is treated?
If it is ST elevated or not
How do you manage symptoms?
GTN/opiates
GTN infusion?
Seek help if pain worsening or heart failure
What risk factors can be modified post event?
Advise to stop smoking
Identify and treat diabetes mellitus, hypertension, hyperlipidemia
Advise a diet high in oily fish fruit, vegetables and fibre and low in sat fats
Encourage exercise and do cardiac rehab
Flag mental health to GP if suspected anxiety or depression