5 Flashcards
4 common symptoms of menopause
Hot flashes
Vasomotor symptoms
Atrophic vaginitis
Dyspareunia
What is benefit in HT for menopausal woman?
Prevention of osteoporosis, relief of vasomotor symptoms and atrophic vaginitis
5 reasons not to use HT in menopausal women?
1Cmbined estrogen and progestogen use beyond three years increases the risk of breast cancer.
- Use of unopposed systemic estrogen in women with a uterus increases endometrial cancer risk.
- Beginning HT after age 60 increases the risk of coronary artery disease.
- HT increases the risk of stroke at least for the first one to two years of use.
- HT for menopausal symptoms should use the lowest effective doses for the shortest possible times.
Can HT increased risk of CAD and stroke?
YES
If you want to start HT, how can you decrease risk of endometrial cancer?
combined HT, unopposed estrogen is dangerous for endometrial growth
What age range is mammogram testing recommended?
50-74, every two years (shared decision making if to begin at 40 based on family history, risk factors, patient preference)
Age range for colon screening
50-75
When to do co-test pap smears?
30-65; co-test is every 5 years, could opt for cytology alone every 3 years
When can a woman stop having paps?
> 65 years old with two previously negative pap smears
When to screen for osteoporosis?
> 65 or woman younger with risk of > 65 year old based on calculator
A post-menopausal woman comes in with vaginal bleeding. What is on your differential?
Endometrial hyperplasia or cancer, proliferative endometrium, cervical polyps, hormone producing ovarian tumors
What are the risk factors for endometrial cancer?
•unopposed estrogen therapy •tamoxifen (Nolvadex) - Often used in women with breast cancer and has an estrogenic effect on the female genital tract. •obesity •anovulatory cycles •estrogen-secreting neoplasms •early menarche (before age 12) •late menopause (after age 52) •menstrual cycle irregularities •nulliparity age hypertension history of breast, colon cancer diabetes
What should be included in workup of postmenopausal bleeding?
CBC
TSH
Transvaginal US
Endometrial biopsy
What is a reassuring endometrial thickness?
<4/5 mm
What is the calculator used for osteoporosis risk?
FRAX score; helps determine if a women under 65 should get DEXA scan. If FRAX score is > 10% then advise for screening.