4 Flashcards
Who should be screened for chlamydia?
All sexually active women age 24 and younger
Sexually active women age 25 and older who are at increased risk`
What is sensitivity?
is the proportion of patients with disease who test positive. False Negative rate among those with disease = (1-Sensitivity).
If a person is rubella non-immune and wants to conceive, how long should they wait after recieving immunization?
patient must wait three months before conceiving to provide adequate protection from embryonic and/or fetal complications.
When to immunizae against influenza?
flu season October through March
What are the general groups of birth control available?
oral contraceptives, medroxyprogesterone (Depo-Provera) injections, transdermal options, IUDs, and the vaginal ring (NuvaRing)
How much folic acid should a healthy mom take? What if she has diabetes or cerebral palsy? What if there’s a history of neural tube defects?
1) normal = 400-800 micrograms
2) 1 mg in patients with diabetes or epilepsy
3) 4 mg in patients who bore a child with a previous neural tube defect
What are 3 diseases you may want to do carrier screening based on family’s ancestry/background?
sickle cell anemia thalassemia Tay-Sachs disease cystic fibrosis nonsyndromic hearing loss (connexin-26)
What are the main medical diseases to manage pre-conception and in pregnancy?
Diabetes: optimize control, folic acid, 1 mg per day, off ACE-inhibitors
Hypertension: avoid ACE inhibitors, angiotensin II receptor antagonists, thiazide diuretics
Epilepsy: optimize control; folic acid, 1 mg per day
DVT: switch from warfarin (Coumadin) to heparin
Depression/anxiety: avoid benzodiazepines
When and why can bleeding occur early in pregnancy?
around the time of the missed menses as a result of an invasion of the trophoblast into the decidua (implantation bleed)
How do we test for chlamydia?
Urine PCR
A girl recieved the live varicella vaccine before knowing she was pregnant. Is it likely the baby will have defects?
NO, never been reported. However, infection with chicken pox during pregnancy has been associated with defects
Why order a CBC prenatally?
detect various nutritional and congenital anemias, and to detect platelet disorders.
What two routine immunizations are live and should not be used in pregnancy?
MMR/rubella and varicella
What do you need to do for a patient who is bleeding in pregnancy, regardless of how far along she is?
50mcg dose of Rho(D) Immune Globulin (e.g., RhoGAM) in first trimester, 300 mcg 28 and beyond
What is the first vital sign to reflect loss of blood?
heart rate… can take some time and blood loss for blood pressure changes
What is ectropion?
When the central part of the cervix appears red from the mucous-producing endocervical epithelium protruding through the cervical os, onto the face of the cervix. It has no clinical significance and is common in women who are taking oral contraceptive pills.
What labs are recommended to evaluate first trimester bleeding?
1) Complete blood count (CBC)
2) PCR for gonorrhea and chlamydia
3) Wet mount preparation
4) Progesterone
5) Quantitative beta-human chorionic gonadotropin (quant. beta-hCG)
What does wet mount evaluate?
Trichomonas, yeast, clue cells for bacterial vaginosis
What’s the role of progesterone in diagnosing miscarriage?
Laboratory testing for progesterone is most useful in extreme situations. If the result is >25, it is highly associated with a sustainable intrauterine pregnancy. If the result is <5, it is highly associated with an evolving miscarriage or ectopic pregnancy. Levels between 5 and 25 have minimal diagnostic value in distinguishing intrauterine from ectopic pregnancy.
How does bHCG increase in early pregnancy?
doubles every 48 hours for the first 6-7 weeks of gestation
What do you expect on US and with bHCG for 5 weeks gestation?
gestational sac is visible on vaginal sonography and the β-hCG should be about 1398 (+155) mIU/mL