5-6. Strabismus I + II Flashcards

1
Q

Strabismus is the ... in the presence of a full opportunity to ... (i.e. one visual axis is ...). This is different from phoria because phoria is .... There are other words/ phrases that means strabismus: ....

A

Strabismus is the misalignment of one visual axis from fixation in the presence of a full opportunity to fuse (i.e. one visual axis is not directed at the object of interest). This is different from phoria because phoria is the misalignment of one visual axis from fixation when the opportunity to fuse is removed, but accurate alignment when fusion is allowed. There are other words/ phrases that means strabismus: squint, heterotropia, tropia, cross-eyed, wall-eyed.

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2
Q

What is sensory fusion?

A

The ability of the eyes to contribute to the binocular percept.

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3
Q

Fusion is thought to have 3 levels:
... (1st degree fusion) = being aware of an input into each eye that is ... e.g. ... ∴ ...;
... (2nd degree fusion) = being aware of an input into each eye that is ... e.g. ...;
... (3rd degree fusion) = being aware of ... due to stimilulation of ....
Clinically this is the common way to measure .... E.g. Contour stereopsis using ... & Randot stereopsis using ....

A

Fusion is thought to have 3 levels:
Simultaneous perception (1st degree fusion) = being aware of an input into each eye that is different e.g. Maddox rod + touch ∴ see a line and dot at the same time;
Superimposition (2nd degree fusion) = being aware of an input into each eye that is similar and in the same position e.g. Howell phoria card;
Stereopsis (3rd degree fusion) = being aware of depth due to stimilulation of disparate receptors.
Clinically this is the common way to measure measure fusion. E.g. Contour stereopsis using Titmus Fly & Randot stereopsis using Titmus Randot.

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4
Q

Motor fusion can be described as the ability to .... It is measured with .... It can also be analysed using instruments that ..., such as ... or ....

A

Motor fusion can be described as the ability to maintain motor alignment to achieve sensory fusion. It is measured with prisms in free space. It can also be analysed using instruments that present targets to each eye and can change vergence demand, such as synoptophore or red-green anaglyphs.

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5
Q

What are the causes of strabismus?

A

Strabismus develops due to an imbalance between factors that increase the demands on fusion and factors which improve the quality of fusion. If there is more demand on fusion, there will be strabismus.

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6
Q

What are the factors that increase the demand on fusion?

A
  • High refractive error - especially high hyperopia causing ET (>+3DS = high risk of ET)
  • Abnormal innervation e.g. high AC/A ratio = ET at near only; CNIII palsy = affected eye turn down and out
  • Eye muscle disturbance e.g. congenital malinsertion of EOM
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7
Q

What are the factors that decrease the quality of fusion?

A
  • Congenitla lack of fusion → nearly always causes an infantile ET & occasionally infantile XT
  • Reduced VA in one eye ∵ anisometropia (particularly hyperopic), amblyopia (compensatory development), macula dystrophy/ disease
  • Peripheral retinal disease
  • Nystagmus
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8
Q

The objectives of a strabismus assessment is to ascertain ... of the strabismus. We should specifically ask for ...;
To describe the ... of the strabismus, including the ... and ... of the eyes under various circumstances;
To describe the ... of the strabismus. The visual function of each eye need to be described when ... and when ....
... is a common ... consequence of strabismus.
... or ... are common ... consequences of strabismus.

A

The objectives of a strabismus assessment is to ascertain the px's and the family's knowledge of the strabismus. We should specifically ask for descriptive information and the family's awareness of the problem;
To describe the motor aspects of the strabismus, including the positions and movements of the eyes under various circumstances;
To describe the sensory aspects of the strabismus. The visual function of each eye need to be described when used separately (monocular) and when used together (binocular).
Amblyopia is a common monocular consequence of strabismus.
Suppression or Diplopia are common binocular consequences of strabismus.

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9
Q

History taking is important in a strabismus assessment:
* ...? → we need to know how aware the parents are with this & also show the parents .... If the parents can describe how the eyes turn, we can find out which eye is the ....
* ...? → if has been week, it is preferred because there is ...; if has been months, it may be ....
* Is there a Hx of ...? → ... are indicative of increase in ..., which should be triagely ....
* Is there a Hx of ...? → should be walking by ... & talking by ... -> there is ....
* ... for this strabismus? → anything’s been tried and given up?
* Is there ... of strabismus → Hyperopia & strabismus is highly ... - No FHx = ...%; FHx = ...%. If there is ET in immediate family, there is ...% chance of a child being ET; ...% would be over +4.00DS at 1 yo & ...% of these hyperopes would have ET.

A

History taking is important in a strabismus assessment:
* What do the parents see? → we need to know how aware the parents are with this & also show the parents how their child's eyes are different. If the parents can describe how the eyes turn, we can find out which eye is the more habitual fixating eye
* How long has the strabismus been present? → if has been week, it is preferred because there is less adaptations; if has been months, it may be problematic to treat and observe due to adaptations.
* Is there a Hx of significant falls/ loss of consciousness/ significant illness (headaches most days, nausea)? → Headaches are indicative of increase in intracranial pressure, which should be triagely referred. Is there a Hx of developmental delay? → should be walking by age 12 months & talking by age 24 months (50+ words) -> there is higher incidence of strabismus in children with multiple neurological problems.
* Has there been any treatments given for this strabismus? → anything’s been tried and given up?
* Is there family Hx of strabismus → Hyperopia & strabismus is highly hereditary - No FHx = 2%; FHx = 30%. If there is ET in immediate family, there is 17% chance of a child being ET; 38% would be over +4.00DS at 1 yo & 46% of these hyperopes would have ET.

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10
Q

The prognosis for a cure of stabismus is poorer if it were an ... (before ... yo) or ... between the .... and ....

A

The prognosis for a cure of stabismus is poorer if it were an early onset (before 2 yo) or long delay between the age of onset and first treatment (6 months).

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11
Q

Of all ET presentations, there are ...% that are psuedo-strabimus in Caucasians. Some children may appear to have ET on causal inspection but .... This is commonly caused by ..., where the ... is less visible than ... in each eye. This must be ruled out using ..., ..., ..., ... and ....

A

Of all ET presentations, there are 50% that are psuedo-strabimus in Caucasians. Some children may appear to have ET on causal inspection but eyes are straight with cover test. This is commonly caused by epicanthal folds, where the nasal sclera is less visible than temporal sclera in each eye. This must be ruled out using Hirschberg test, cover test, stereopsis, equal acuity and normal cycloplegic refraction.

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12
Q

What are the motor aspects needed to be addressed in a strabismus assessment?

6 aspects

A
  • Detection of strabismus: Is there misalignment?
  • Direction of strabismus?
  • Magnitude of strabismus?
  • Laterality: which eye fixates, and which eye has the strabismus?
  • Comitancy: does the magnitude of the strabismus change with gaze direction?
  • Distance near incomitance
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13
Q

What are the 4 things that we should use to describe a strabismus?

A
  • Constancy → is it intermittent? (Most XT are intermittent; most ET are constant)
  • Direction → Eso = in; Exo = out; Hyper = up; Hypo = down
  • Laterality → which eye? Alternating?
  • Comitancy → Comitant = same magnitude in all directions of gaze
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14
Q

Describe how a Hirschberg’s test is performed. What are the expected results in different situations?

A

Situate 50cm away from px and shine a pen torch between the eyes of the px. Observe the corneal reflexes from the eye. If there is no strabismus, reflexes will be symmetric and about 0.5mm nasal to the pupil centre. In ET, the reflex on the fixating eye will be normal, but the reflex on the ET eye will be temporally displaced. If there is XT, the reflex on the XT eye will be nasally displaced.

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15
Q

Cover test is the ... for strabismus, particularly for .... The macula has ... superiority. Therefore when a deviated eye is uncovered and the non-deviated eye is covered, ... with the macula of the ....
... movement occurs when the deviated eye moves to pick up fixation, the non-deviated eye moves under cover in the ....

A

Cover test is the most sensitive test for strabismus, particularly for motor evaluation. The macula has sensory and motor superiority. Therefore when a deviated eye is uncovered and the non-deviated eye is covered, the deviated eye fixates onto the target with the macula of the deviated eye.
Yoked movement occurs when the deviated eye moves to pick up fixation, the non-deviated eye moves under cover in the same direction.

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16
Q

What does a unilateral cover test tell you?

A

Tells you if a strabismus is a phoria or a tropia, and also the direction of the turn. If a tropia is found, the cover test also tells you whether the turn is unilateral or alternating. This also tells you which eye is the fixating eye. Lastly, it can help distinguish between a forced or true alternation.

17
Q

What are the differences between a true alternation and a forced alternation?

A

Forced alternation occurs when one eye has better VA than the other, where the better eye is forced to fixate due to better quality of image. This occurs with amblyopia. True alternation is when both eyes have at least 6/6 VA, they alternate not for better vision.

18
Q

What are the differences between ET and XT?

A

ET is Esotropia, where the eyes are converged too much for the object of interest, and fusional divergence is unable to achieve fusion, resulting in diplopia.
XT is Exotropia, where the eyes are diverged too much for the object of interest, and fusional convergence is unable to achieve fusion.

19
Q

How is the size of a strabismus specified?

A

In Prism dioptre (pd). 1 pd = 1 cm deviation at 100cm (2pd = 1 degree). The amount of prism required to neutralise the strabismus defines the size of teh strabismus in prism dioptres.

20
Q

Can you estimate the magnitude of strabismus using Hirschberg test? If yes, how?

A

Yes, we can use the eye’s anatomy to estimate in prism dioptres.
* 1mm displacement of reflex = 22pd.
* Within the pupil = small deviation;
* Pupil margin = 15pd medium deviation;
* Mid iris = 30pd;
* Near limbus = 45 pd large deviation.
Combining Hirschberg with Krimsky can increase the accuracy as prisms are used to move the corneal reflex.

21
Q

What is the most accurate way of measuring the magnitude of deviation in children? Describe how you would conduct this test?

A

Alternating cover test with prism neutralisation.
Place prisms in the spectacle plane of the fixating or strabismic eye, repeat the alternating cover test, adjust the prism power until you do not see any movement. Add a bit more until reversal. The prism power for neutralisation of the movement is the size of the strabismus. BI prisms for ET; BO for XT; BD for HyperT.

22
Q

What is an accurate way of measuring the magnitude of deviation in adults? Why is it sometimes not preferred?

A

Maddox Rod. May not be useful due to sensory adaptations e.g. suppression

23
Q

What is the preferred method of finding the magnitude of phoria ?

A

Howell Phoria card.

24
Q

Unilateral strabismus is when ...; True alternating strabismus is when ...;
Forced alternating strabismus ....

A

Unilateral strabismus is when when one eye is always used for fixation; True alternating strabismus is when either eye freely fixates; Forced alternating strabismus is when the strabismus eye fixates at times on cover test.

25
Q

Px who has strabismus but who can hold fixation with either eye is called .... For a true alternating strabismus, px requires ..., meaning that each macula .... Px with unilateral strabismus will often (but not always) have ... in the strabismic eye.

A

Px who has strabismus but who can hold fixation with either eye is called alternating strabismus. For a true alternating strabismus, px requires equal acuity in each eye, meaning that each macula has equal sensory superiority. Px with unilateral strabismus will often (but not always) have amblyopia in the strabismic eye.

26
Q

How is the comitancy of the strabismus assessed?

A

Observe if the magnitude of strabismus change with changing alignment in 9 positions of gaze using a pen torch. using Hirschberg and sometimes with cover test at distance. Record findings in a grid.

27
Q

What is a comitant strabismus and incomitant strabismus?

A

Comitant strabismus has the same magnitude in all directions of gaze. Incomitant strabismus varies by 10pd or more in different positions of gaze.

28
Q

What are the common causes of incomitances with strabismus?

10 causes

A
  • CN4 palsy
  • Muscle malinsertion or early disturbances of fusion (A & V patterns)
  • High AC/A ratio (convergence excess, near>distance)
  • CN6 palsy (acquired and congenital = Duane’s)
  • Vertical incomitance in R-L gaze
  • Horiontal incomitance in up-down gaze
  • Horizontal incomitance in near-far fixation N>D
  • Minor horizontal incomitance & significant near far incomitance D>N
  • Profound abduction deficit with minimal distance near incomitance
  • Browns syndrome
29
Q

What is Duanes syndrome?

A

CN6 palsy (SO4 LR6 All3), therefore lateral rectus is paralysed and the eyes cannot abduct. Left Duanes: When looking to the right, right eye adducts, but left eye will fail to abduct.

30
Q

If the superior rectus pulls the eye up, why does the superior oblique pull the eye down?

A

SO is attached behind the equator, therefore it pulls the eye down instead. SR is attached to the top of the eye.

31
Q

What should be done if there is a change in vertical deviation during excursion? (Vertical incomitant strabismus)

A

Use the Park’s Three Step Test

32
Q

The Park’s Three Step Test is used for .... A ... should also be used to aid diagnosis.
Step 1 is to find the .... If the right eye is higher, then ... or .... ... on the diagram.
Step 2 is to find whether .... If it is ..., then one of the two right gaze elevators are not working or .... Circle!
Step 3: Is the ...?. Circle the diagonal muscles which .... If it is worst in right tilt, ... is the only muscle circled 3 times, therefore .... This can be due to ....

A

The Park’s Three Step Test is used for vertically incomitant strabismus. A diagnostic action field diagram should also be used to aid diagnosis.
Step 1 is to find the hypertropic eye in primary gaze. If the right eye is higher, then one of the two depressors are not working or one of the two left eye elevators are not working. Circle these muscles on the diagram.
Step 2 is to find whether hypertropia is worse in left or right gaze. If it is worst in left gaze, then one of the two right gaze elevators are not working or one of the two left gaze depressors are not working. Circle!
Step 3: Is the hypertropia worst when the head is tilted to the left or to the right?. Circle the diagonal muscles which match the direction of the midline of the face when the hypertropia is worst. If it is worst in right tilt, the right superior oblique muscle is the only muscle circled 3 times, therefore this is the pareti muscle. This can be due to CN4 (trochlea) nerve palsy or othe simulating lesions.

33
Q

What are the 3 Golden Rules of Pratt Johnson?

A
  1. Superior oblique palsy until proven otherwise
  2. Congenital until proven otherwise
  3. Px usually don’t fixate with the eye that has a palsy
34
Q

In ET, the deviation at near is often the same as distance. Sometimes near deviation is worse (greater than 10pd), what is this called? What is it caused by? What can be used to treat this?

A

Convergence excess esotropia. This is almost always caused by high AC/A ratio. This responds to plus addition.

35
Q

Why are bifocals preferred to correct accommodative esotropia with convergence excess?

A

Bifocals are preferred over multifocals because px often require a big add and require a large portion of it. The near segment should be placed at the bottom edge of the pupil.

36
Q

In ET, distance deviation may sometimes be worse than near, what is this called? What is it caused by?

A

Divergence insufficiency.
Usually caused by acquired CN6 palsy which innervates lateral rectus, therefore there is an abduction deficit. This is often caused by intracranial pathology that inrcreases intracranial pressure (papilloedema, headaches, DV) → requires ophthalmologist referral urgently