5

Question 1

What makes up the White pulp

Answer 1

Central arteriolar with a periarteriolar lymphoid sheath
Peri follicular zone with a
Germinal centre inside surrounded by B cell corona surrounded by marginal zone

Question 2

Where does blood flow from the trabecular artery

Answer 2

Central arterioles
Partially through follicle to edge of marginal zone
Shunted to venous sinuses
Some leave vessel bed and end up in trabeculae network of peri follicular zone

Question 3

What’s the red pulp between the sinuses called

Answer 3

Cords

Question 4

What are the cords

Answer 4

reticular network filled with immature cells and red blood cells making their way to sinuses

Question 5

How does the structure of the sinus walls help eliminate old rbcs

Answer 5

Narrow gaps stiff or old cells can’t fit through

Removed by macrophages

Question 6

In the sinus what are the two functions of a macrophage

Answer 6

Kill/clean up dead or old cells

Recycle the iron

Question 7

How do mz B cells help bridge the immunological gap

Answer 7

Can differentiate into plamsbasts without T cell activation within hours

Question 8

What are the two routes of blood in the spleen

Answer 8

90% directly into venous sinus from capillaries

10% through open ended sheathed capillaries into peri follicular zone and then to red pulp