5 Flashcards
Over the past two weeks, several pigs in a herd have been febrile and depressed. Many were constipated, then had diarrhea.
A few were incoordinated and one had seizures. A few have died. Necropsy revealed petechial hemorrhages on the kidneys and larynx, and a hemorrhagic urinary bladder.
Of the following choices, which one is most consistent with a presumptive diagnosis?
Classical swine fever
Erysipelas
Glasser’s disease
Streptococcus suis infection
Swine dysentery
A one-month old foal develops fever, icterus, and diarrhea acutely. Bloodwork shows hyperfibrinogenemia, hypoglycemia, and elevated liver enzymes. Which of these conditions is most likely?
Herpesviral hepatitis
Theiler’s disease
Tyzzer’s disease
Clostridium novyi type B
The correct answer is Tyzzer’s disease. This is the most likely cause because of the age of the foal and the acute nature of the disease. Tyzzer’s disease is caused by Clostridium piliformis, which causes an acute necrotizing hepatitis. It affects only foals from about 1-6 weeks of age. Theiler’s disease is a condition of adult horses. Clostridium novyi is rare in horses and seen much more in sheep and cattle. Herpesvirus can cause hepatitis but is usually seen at or very soon after birth.
A two-year-old Angus cow is presented with weakness of the hind limbs and a staggering gait.
On physical exam, the heart rate and respiratory rate are slow and irregular, and the pupils are dilated.
The cow’s breath and urine smell like the odor of mouse urine.
Suddenly the cow’s pulse becomes rapid and thready, she collapses, and dies of apparent respiratory failure.
Which one of the following plants is most likely to have caused this spectrum of clinical signs?
A- Pinus ponderosa (Western yellow pine)
B- Veratrum spp (False hellebore, Skunk cabbage)
C- Tetradymia spp (Horsebrush)
D- Conium maculatum (Poison hemlock)
E- Centaurea spp (Knapweed, Yellow star thistle)
An 11-year old female Pomeranian presents to you for coughing and exercise intolerance. On exam: Wt: 9.25 lbs, T: 101.2F (38.4 C), HR: 132 bpm, RR: Panting, mucous membranes are pink. She has mild tracheal sensitivity and a grade III-IV/VI left apical holosystolic murmur and grade II/VI right apical holosystolic murmur. Femoral pulses are strong and synchronous, with a regular rhythm. She has harsh lung sounds bilaterally. On abdominal palpation, you note hepatomegaly. You find bilateral luxating patellas. You take chest radiographs (see image) and decide to treat the dog based on these findings. Which medication plan is most appropriate?
Furosemide and enalapril
Clavamox and enrofloxacin
Immiticide (Melarsomine)
Atropine and a temporary pacemaker
Oxygen and atenolol
The radiograph here shows a severe symmetrical alveolar pattern in the perihilar region extending to the right and left caudal lung lobes. The heart is tall on the lateral view causing dorsal elevation of the trachea.
This, in conjunction with the physical findings, is compatible with congestive heart failure (CHF) secondary to mitral valve regurgitation. The dog also has hepatic congestion evident by enlargement on the radiograph. Treatment for CHF include diuretics (furosemide/Lasix, hydrochlorothiazide, spironolactone), arterial vasodilators (enalapril, benazepril, amlodipine, hydralazine), positive inotropes (pimobendan), and venodilators (nitroglycerine).
Clavamox and enrofloxacin are antibiotics which could be used to treat pneumonia, but that is not this dog’s problem. Immiticide is the treatment for heartworm. Atenolol is a beta blocker and not part of the management of mitral regurgitation or CHF. Atropine or a pacemaker would be indicated for conduction problems.
Annotations:
There is marked elongation of the cardiac silhouette on the lateral views (yellow line) resulting in dorsal displacement of the trachea (red area), consistent with left ventricular enlargement.
A large focal bulge is noted at the caudodorsal aspect of the cardiac silhouette consistent with left atrial enlargement. (Purple circle)
A focal soft tissue opaque bulge is also noted in the region of the left auricle on the DV view. (Pink circle)
There is concurrent mild widening of the cardiac silhouette on the lateral views consistent with right-sided cardiomegaly (orange line).
The cranial lobar pulmonary veins are larger than the corresponding arteries. There is mild distension of the caudal lobar pulmonary arteries and veins with right caudal lobar pulmonary vein slightly larger than the corresponding artery. (green lines)
There is a marked diffuse unstructured interstitial pattern to early alveolar pattern (blue circle), most severe in the dorsal aspects of the right caudal and left caudal lung lobes.
The liver is mildly enlarged, extending beyond the costal arch with rounded caudoventral margins. (brown circle)
Radiographs provided by Adrien Hespel, DVM, MS, DACVR and University of Tennessee College of Veterinary Medicine
An outbreak of diarrheal disease of piglets has occurred which affected the healthiest animals in the herd, one to two weeks after weaning.
Some affected piglets had no signs except peracute death.
Other affected piglets exhibit diarrhea, ataxia, paralysis, and recumbency.
What condition is at the top of the differential diagnosis list?
Epidemic transmissible gastroenteritis (TGE)
Streptococcus suis
Clostridium perfringens type C enteritis
Edema disease
Porcine proliferative enteritis
A 6-month old cat presents for having ptyalism and for being underweight. On physical examination, you note a bright copper color to the cat’s iris bilaterally. What is this suggestive of?
Hemolytic anemia
Portal systemic shunt
Polycystic kidney disease
Toxoplasmosis
The correct answer is a portal-systemic shunt. Ptyalism is a sign commonly seen with PSS in cats but not dogs, and the copper-colored iris is a striking and almost pathognomonic finding in conjunction with other clinical findings. Hemolytic anemia could cause icterus but not the change in iris color. Animals with polycystic kidney disease would not have a copper-colored iris. Toxoplasma can cause ocular signs such as uveitis but would not have a copper iris.
Which one of the following choices includes the cardinal sign of trigeminal neuritis?
A- Inability to close the mouth
B- Dysphagia, dysphonia and stridor
C- Circling and head tilt toward side of lesion, no other signs
D- Masseter muscle pain associated with chewing
E- Paralyzed eyelid, ear or lip on one or both sides of the face
Which of these are used in the minor cross match for blood products when looking for a compatible blood donor for a dog?
A- Recipient red blood cells, donor plasma
B- Donor red blood cells, donor plasma
C- Recipient red blood cells, recipient plasma
D- Donor red blood cells, recipient plasma
The correct answer is recipient red blood cells, donor plasma. In a minor crossmatch, you are looking to see if the factors in the plasma of the donor are going to react to the recipient’s red blood cells.
What condition is associated with rectal stricture in pigs?
Salmonella typhimurium
Rotavirus
Coccidiosis
Intussusception
Intestinal spirochetosis
A 6-year old male neutered Weimaraner presents for right forelimb lameness. Radiographs are shown below and show a mixed productive and destructive lesion affecting the right distal radius with accompanying soft tissue swelling. The lesion does not cross the joint. What is the most common primary bone tumor in the dog?
Fibrosarcoma
Multiple myeloma
Chondrosarcoma
Hemangiosarcoma
Osteosarcoma
The correct answer is osteosarcoma. Chondrosarcoma, fibrosarcoma and hemangiosarcoma can all be primary bone tumors but are much less common in dogs than osteosarcoma.
Annotations:
Yellow: Amorphous periosteal proliferation
Orange: Geographic lysis and expansile appearance of the mid-radius
Blue: soft tissue swelling
A nine-year-old Irish setter is presented for vomiting.
The owner states that the dog does not really retch, but just spits up food soon after eating.
The dog is normal otherwise.
Based on the lateral radiograph below, which one of the following choices is the most likely diagnosis?
Persistent right aortic arch
Gastric foreign body
Megaesophagus
Mediastinal mass
Pulmonary bullae
Which of these nerve blocks is used to examine the eyes of a horse?
Oculomotor nerve block
Trigeminal nerve block
Auriculopalpebral nerve block
Corneal nerve block
The correct answer is auriculopalpebral nerve block. Blocking this branch of cranial nerve VII (facial nerve) disrupts the motor innervation to the orbicularis oculi, which is the muscle that closes the eye. In the horse, this muscle is very strong and can prevent a thorough ocular exam. To perform this block, lidocaine is injected subcutaneously at the caudal aspect of the zygomatic arch where the nerve is palpable. Because this is a motor nerve, the eye will not be able to close as well, but there is no anesthesia of the tissue.
A two-year-old male neutered domestic shorthair cat is presented after a suspected fall from a height of approximately 35 feet (over ten meters).
The cat is initially stabilized with intravenous fluids and oxygen therapy. Four hours later, the cat has not urinated and no urinary bladder is palpable.
An abdominal focused assessment with sonography for trauma, triage, and tracking (AFAST) reveals a moderate volume abdominal effusion, with no visible urinary bladder.
What test would confirm the top differential?
A- Abdominocentesis with Gram stain and cell count
B- Total protein and microscopic analysis of the ascites
C- Lactate and glucose levels of peritoneal sample and blood
D- Measurement of BUN in blood and fluid
E- Paired plasma and effusion potassium and creatinine
A horse presents to you with a corneal ulcer. You are concerned because it appears to be infected, as shown in this image. You perform cytology and find gram negative rods. What is the most likely organism infecting the corneal ulcer in this horse?
Pasteurella multocida
E. coli
Staphylococcus spp.
Pseudomonas
The correct answer is Pseudomonas. Pseudomonas is the most common agent causing bacterial keratitis in the horse. The gram negative cytology provides further evidence that it is the likely culprit. Staphylococcus can cause keratitis in horses but is gram positive. E. coli and Pasteurella are not agents that are commonly involved with keratitis in the horse.
Which group is most at risk of developing the lesion evident in this image?
A- Young horses ingesting Perilla mint; Standardbreds
B- Cattle without reticular magnets; Charolais
C- Obese cats, any breed; Burmese cats
D- Old, small-breed dogs; Cavalier King Charles Spaniel
E- Sheep or goats pastured above 2000 meters; Saanens
A 10-year old male castrated cat that you have previously diagnosed with hyperthyroidism presents to you for acute onset of blindness. You perform an ophthalmic exam and note retinal hemorrhage. What diagnostic test should you perform first?
Coagulation times
Free T4 levels by equilibrium dialysis
Serum BUN and creatinine
Total T4 levels
Blood pressure
The correct answer is blood pressure. Cats with hyperthyroidism are likely to develop hypertension. If this is severe enough (>180-200 mmHg systolic), they can be at risk for acute retinal detachment or hemorrhage resulting in blindness. Prompt resolution of the hypertension is critical to prevent further damage to the eye and other organs.
A middle-aged, depressed, coughing, exercise-intolerant Doberman pinscher is presented.
The dog has a rapid and irregular heart rate.
Which initial diagnostic step is most appropriate?
A- Ultrasound for pericardial effusion
B- Thoracic radiographs to evaluate for congestive heart failure
C- Abdominal focused assessment with sonography for triage, trauma, and tracking rapid (AFAST) for hemoabdomen
D- CBC to identify anemia
E- Bronchoscopy for airway assessment
A three-year-old white rat is presented with yellowing fur and a brownish, granular sebaceous secretion at the base of affected hair shafts.
What should the owner be told?
A- Normal age-related change
B- Probable ringworm, resolves spontaneously with sunlight exposure
C- Moisture-related dermatitis, cage needs more frequent cleaning
D- Staph dermatitis, responsive to antiseptic shampoo
E- Common manifestation of chorioptic mange
A 6-year old female spayed English Pointer presents for lethargy and weight gain. The owner notes that the dog is eating and drinking a normal amount, but the dog is still gaining weight. A physical exam reveals weak pelvic limbs, facial nerve paralysis, a symmetrically patchy haircoat, and seborrhea. Lab work reveals a normocytic, normochromic anemia with a PCV of 29% (35-57%), lipemic serum, and cholesterol of 1090 mg/dl (135-278 mg/dl). What is the most likely diagnosis?
Hypothyroidism
Pituitary dependent hyperadrenocorticism
Hyperthyroidism
Adrenal dependent hyperadrenocorticism
The correct answer is hypothyroidism. The clinical signs, physical exam findings, and lab work abnormalities are classical for hypothyroidism. Other common abnormalities seen with hypothyroidism include pyoderma, neuromuscular signs (ataxia, knuckling, vestibular signs, etc), markedly elevated triglycerides, and a mild normocytic, normochromic anemia. Hyperthyroidism rarely occurs in dogs. You would expect to see polyuria, polydipsia, and polyphagia with hyperadrenocorticism.
A five-year-old female spayed domestic short-haired cat is presented with chronic vomiting, anorexia, and weight loss.
Physical examination reveals icterus, dehydration, and fever.
Thickened small intestinal loops are appreciated with abdominal palpation, and serum biochemistry shows increased bilirubin and liver enzymes.
The cat is diagnosed with extrahepatic biliary obstruction with accompanying cholangitis and inflammatory bowel disease.
Which one of the following normal anatomic features may predispose cats to this triad of diseases?
A - Narrowing of the duodenum distal to the entry of the common bile and pancreatic ducts
B - Enlarged duodenal papilla in comparison to other species
C - Decreased proportion of alpha-smooth muscle actin in muscle fibers of the wall of the gall bladder in cats
D - Common opening of the pancreatic and common bile ducts into duodenum
E - Decreased diameter and increased branching of the hepatic ducts in comparison to other species
You are visiting a small “back-yard” flock of chickens and examining the animals. You find several small gray-red mites (approx 0.7 mm) on several of the chickens which you recognize as Dermanyssus gallinae and Ornithonyssus sylviarum. How are these mites best controlled?
A- Control of both Dermanyssus gallinae and Ornithonyssus sylviarum relies on thorough insecticidal treatment of the environment
B- Control of both Ornithonyssus sylviarum and Dermanyssus gallinae relies on application of approved pesticides to affected birds
C- Ornithonyssus sylviarum is controlled primarily by thorough insecticidal treatment of the environment and Dermanyssus gallinae must be controlled by application of approved pesticides to affected birds
D- Dermanyssus gallinae is controlled primarily by thorough acaricidal treatment of the environment, and Ornithonyssus sylviarum must be controlled by application of approved pesticides to affected birds.
Dermanyssus gallinae (the common red mite) maintains the majority of the population in the environment so it is important to monitor and treat the environment including the cracks and crevices where mites tend to reside. Ornithonyssus sylviarum mites (northern fowl mites) spend their entire life cycle on the bird. This allows them to multiply more rapidly and makes it essential to treat the birds themselves to control the problem.
What is the earliest stage post-breeding that an experienced practitioner can reliably rectally palpate fremitus in the uterine artery of the gravid uterine horn in a pregnant cow?
A - 90-120 days
B - 60-75 days
C - 120-150 days
D - 70-80 days
E - 45-60 days
Which of these is an adrenergic vasopressor in dogs?
Dopamine
Atropine
Hydralazine
Glycopyrrolate
The correct answer is dopamine. Adrenergic vasopressors are frequently used to treat hypotension during anesthesia. Drugs in this category are dopamine, dobutamine, ephedrine, phenylephrine, and norepinephrine. Atropine and glycopyrrolate are anticholinergic drugs. Hydralazine is a vasodilator used to treat hypertension.
Which diseases are associated with a high anion gap (AG)?
A - Grain overload, ethylene glycol toxicity, renal failure
B - Hypercalcemia of malignancy, hypoadrenocorticism, displaced abomasum
C - Eosinophilic enteritis, hypothyroidism, gastrinoma
D - Prostatic adenocarcinoma, pleural effusion, lymphangiectasia
E - Diabetes mellitus, pancreatitis, chronic diarrhea
Several litters of 2 to 3 day old pigs have recently died rapidly with hemorrhagic enteritis. Post mortem lesions include mucosal hemorrhage, necrosis and emphysema in the small intestines. What pathogen is most likely to cause these signs?
Haemophilus parasuis
Erysipelothrix rhusiopathiae
Enterotoxigenic E. coli
Salmonella choleraesuis
Clostridium perfringens type C
The age of these affected pigs along with the rapid course of hemorrhagic and necrotic enteritis help you come to this conclusion. As with many Clostridial diseases, vaccination is the most effective means of control. Other important clostridial diseases of swine include C. perfringens type A, C. difficile, C. tetani, C. botulinum, C. novyi, C. septicum, and C. chauvoei.