5:1:1 Communication and Homeostasis Flashcards
Define homeostasis
The body’s responses to changes in their internal and external environment in order to maintain optimal conditions for enzyme action and cell function
How is the body’s internal environment controlled
Physiological control systems:
- Nervous system
- Endocrine system
What is the nervous system
- Allows us to respond to our surroundings and coordinate and regulate bodily functions
- Information sent through the nervous system as nerve impulses (electrical signals) through neurones
- Neurones coordinate the activity of sensory receptors, decision making centres in the central nervous system, and effectors
What does the nervous system consist of
- Central nervous system (CNS): brain, spinal cord
- Peripheral nervous system (PNS): all nerves in body
What is the endocrine system
- System which has hormone producing glands (endocrine glands), allowing these chemicals to transmit information within the organisms
- Hormones can alter activity of target organs, and used to control functions that don’t need instant responses
Label diagram of the endocrine system in humans
What are the main factors that need controlling in organisms
- Temperature (vital for enzyme activity)
- pH (vital for enzyme activity)
- Blood glucose concentration
Why does pH have to be controlled
- Enzymes have optimum pH’s, and can be denatured at pH extremes
- Denaturing occurs when the H and ionic bonds holding the tertiary protein structure break which alters the shape of the active site
- Enzyme-substrate complex can’t form
Why does blood glucose concentration have to be controlled
- Amount of glucose present affects water potential of the blood and the availability of respiratory substrates for cells
- Usual glucose concentration for humans is 90mg/100cm^3
- Glucose is essential for cellular respiration
Why does the opening/closing of stomata have to be controlled
- Plants require a constant supply of CO2, and well as controlling the water levels in the plant
- Stomata respond to internal and external stimuli (e.g. darkness/water stress)
- Regulation of stomata balances the need for CO2 uptake and water loss
What are negative feedback loops
- A majority if homeostatic control mechanisms use negative feedback to maintain homeostatic balance
- The loops involve:
- A receptor to detect a stimulus
- A coordination system (nervous/endocrine) to transfer the information
- An effector (muscles/glands) to carry out the response
What is the outcome of a negative feedback loop
- The stimulus is continuously monitored
- If there is an increase in the factor, the body responds to make it decrease
- If there is a decrease in the factor, the body responds to make the factor increase
- They reduce the initial effect of the stimulus
What are the two corrective methods used by negative feedback loops to control homeostasis
- One for when the factor becomes too high
- One for when the factor becomes too low
What are positive feedback loops
- Where the original stimulus produces a response that causes the factor to deviate even more from the normal range
- They enhance the effect of the original stimulus
Describe how positive feedback loops work (e.g. bone repair)
- Osteoblasts secrete a hormone called osteocalcin in an inactive form
- The osteoclasts secrete acid which lowers the pH and the acidic conditions to cause the inactive form of osteocalcin to the active one
- The active from of osteocalcin binds to a receptor on beta cells in the pancreas which stimulates then to release insulin
- Osteoblasts have insulin receptors which release more osteocalcin when stimulated
- The osteoblasts cells enhance the effect of the original stimulus (insulin)