48.4 synapses Flashcards
electrical synapses
let the electrical currents flow directly from one neuron to another
how do neurotransmitters get sent across synapses?
1) action potential causes ca2+ to be released into dendrite
2) Ca2+ causes synaptic vesicles to fuse with terminal membrane and release neurotransmitter
3) neurotransmitter diffuses across synaptic cleft
4) it binds to a ligand gated ion channel and opens it
5) makes postsynaptic potential ```
why do we need synapses?
information transfer better regulated
-the neurotransmitter can be regulated by a lot of things
excitatory postsynaptic potentials
-brings closer to threshold
open channels that let Na+ and k+ diffuse
——-makes postsynaptic potential (change in ———membrane potential)
EXCITATORY
inhibitory postsynaptic potentials
neurotransmitters bind to channels for K+ or Cl-
–hyper polarizes membrane
INHIBITS from threshold
temporal summation
when one EPSP passes and
-another EPSP comes without time for first to return to resting
spatial summation
EPSPs produced by different synapses tp the same post synaptic neuron
why is only one EPSP not enough?
- post synaptic do not regenerate as they travel dow the cell
- and they get smaller, the further from the synapse (too far from the dendrite to the axon hillock-where AP is started)