44 – Euthanasia Flashcards
What are the euthanasia AVMA classifications?
- Acceptable
- Acceptable with conditions
- Unacceptable
What makes it an acceptable method? (criteria)
- Consent
- Pain free
- Limit stress
- Safety
- Quick
- Reliable
- Effective: loss of consciousness followed by death
- Irreversibility
- Emotional effect
- Environmental impacts
- *12 criteria in total
Ideal euthanasia: order we want things to be in (process that are occurring in the body)
- Depression of neurons necessary for life function: loss of consciousness (can include anesthesia)
- Hypoxia: cardiac and respiratory arrest
- Physical disruption of brain activity and destruction of neurons necessary for life: LOSS OF BRAIN FUNCTION
What are the options for how to do euthanasia?
- Chemical: inhalant, non-inhalant
- Physical
What are the inhalant agents for euthanasia?
- Isoflurane (irritating)
- Halothane, sevoflurane (non-noxious odour)
- NO increase to speed of onset
- CO: acceptable
- CO2: controversial (acceptable w/conditions)
Inhalant agents: important things to remember/consider
- Chamber method <7kg
o Container needs to be large enough to prevent hypoxia - If can’t get a vein in
- If no injectables available
- Sometimes if during surgery you decide
- Downside: human exposure
- FAST
- Confirmation of death required (heartbeat, breathing, touch cornea and pupils)
- NOT appropriate for reptiles, amphibians, diving birds and mammals (can HOLD THEIR BREATH FOR A LONG TIME)
CO and CO2
- Used for dogs/cats in some humane societies and for rodents and birds
- *Species dependant aversion
CO
- Acceptable
- Signs of agitation, convulsions, muscle spasms, vocalization (can be difficult for the humans involved)
- Source is important (from a tank, not a CAR!)
- Blocks O2 uptake by RBCs
CO2
- Hyperventilate and get acidosis (pain from carbonic acid)
- Breathlessness: panic
- Direct simulation of amygdala: fear response
- 7.5% increases pain threshold (takes time to get there)
- Need 30% to get anesthesia and then followed by death
- *Acceptable with conditions
- Gradual fill recommended
- Ex. used in avian species for depopulation
What are non-inhalant methods of euthanasia?
- Barbiturates
o Pentobarbital - T-61
- Tricaine methane sulfonate (MS-222)
Pentobarbital: things to know or consider
- Rapid, smooth
o Possible excitement and agonal gasp
o Consider adding propofol (or other sedation): premed - Controlled drug
- Must be given IV
- Confirmation of death required
- Risk of scavenging (wildlife, bald eagles and dumps!)
Barbiturates in birds and reptiles
- Most birds anesthetized first otherwise a massive excitement phase
- Reptiles: consider 2-3 days before releasing to owner, intracoelomic acceptable
o 3 chamber heart (difficult on a good day to hear them)
o Can slow heart for extended period of time
o *GOOD TO USE: loss of eye pressure!
T-61
- Contains
o Local anesthetic
o General anesthetic
o Neuromuscular blocking agent - NOT a controlled drug
- *AVMA acceptable, CCAC not recommended
What are the concerns with T-61?
- Improper administration (IV only)
- Pain with administration
- Mammals
o Dysphoria if injected too quickly
o Respiratory paralysis (suffocation) BEFORE loss of consciousness - Birds:
o *does work: Anesthesia immediate + EEG loss <6 secs
Pentobarbital for horses
- IV required
- Sedation or anesthesia recommended (NOT required)
- Risk to scavengers
- *used often
Intrathecal lidocaine AFTER anesthesia in horses
- Longer respiratory, cerebral, brainstem and CV arrest compared IV barbiturates
o Block all neurotransmission out of CNS - Audible heartbeat 5mins vs. <1min
- EEG 2 min vs. 20s
- Sedation required
- *doesn’t matter that it takes longer as they are sedated
- Little risk to scavengers (placed in the intrathecal space which is protected by SC)
Tricaine methane sulfonate (MS-222)
- *Suitable for fish and most amphibians
(if normal for them, need to have access to air until unconsicous) - Sodium bicarb required to buffer (very acidic on its own)
- IMMERSION (terrestrial reptiles should not be fully immersed)
- NOT controlled drug
- Used as an anesthetic
o Increased concentration and prolong exposure - Some reptiles intracoelomic (AVMA vs. unacceptable CCAC)
- Secondary method required to ensure death
What are the unacceptable agents of euthanasia?
- Strychnine, nicotine, caffeine, cleaning agents, pesticides, disinfectants
- Magnesium sulfate, potassium chloride, NM blocking agents
What are the physical methods for euthanasia?
- Captive bolt
- Gunshot
- Cervical dislocation
- Decapitation
- Acceptable with conditions
o Electrocution
o Kill traps
o Thoracic compression
o Exsanguination
o Pithing - *training and skill is CRITICAL
Penetrating captive bolt
- Ruminants, horses, swine, lab rabbits, dogs, birds
- Concussion and trauma to cerebral hemisphere and brainstem
- Adequate restraint is important to ensure proper placement of captive bolt
Cervical dislocation
- Rodents
- Birds
Decapitation
- Rodents for tissue collection
- Wildlife
Koechner euthanizing device
- Squeezes across next and does cervical dislocation
- Longer to death than regular cervical dislocation (more crushing vs. separation)
- Cervical vertebrae fractures
Euthanasia by a blow to the head
- Acceptable for neonatal animals with thin craniums
o Neonates, young piglets, small birds - Single sharp blow delivered to central skull bones with sufficient force can produce immediate depression of CNS and destruction of brain tissue
Gunshot
- Should only be performed by highly skilled personnel trained in use of firearms
- Legal requirements
- Personnel, public and nearby animal safety essential
- *NOT between the eyes: ’x’ between ears and eyes: shot in center of it
o Hard to have correct trajectory - Horse: go from the side (brainstem is at ‘base’ of ear)
Exsanguination should only be considered when (AVMA)
- Animal is unconscious
- BUT: in emergency (ex. mare eviscerated=need to shorten time to death)
Cardiac puncture
- Not acceptable in a conscious animal
- BUT: emergency (ex. deer with only 1 leg=can’t get IV in)