(4.4) Cardiac Pulmonary and Renal Pediatric Pearls 1 (PART 2) (Asthma) [CIS-Newman] Flashcards
What are the essentials of diagnosis of asthma?
- Episodic airflow obstruction
- Reversibility of airflow obstruction
- Sx worse at night or early morning
- Prolonged expirations
- Limitation of airflow
Clinical sx of asthma?
- Cough
- Wheezing
- Chest tightness
- Prolonged exhalation
- SOA
Exposure to _______ can trigger asthma
Exposure to allergens can trigger asthma
Describe the differences in a normal airway vs airway in asthma:
Airway in asthma:
- Lots of mucus production
- immune cell infiltrates
- increased gland production
What are the two hallmark features of prolonged status asthmaticus?
Curschmann spirals
Charcot-Leyden crystals
What occurs in chronic asthma?
Airway remodeling
- THICKENING of the airway wall
- Sub-basement membrane FIBROSIS
- Increased VASCULARITY
- HYPERTROPHY/HYPERPLASIA of the bronchial wall muscle
What is the strongest predisposing factor to asthma?
Atopy
What is the significant difference b/w COPD and Bronchial asthma in terms of FEV1 and FEV1/FVC ratio returning to normal with drug therapy?
COPD = WILL NOT IMPROVE
Bronchial asthma = WILL PROBABLY IMPROVE
**Likely a test question
What does this spirometry likely indicate?
COPD
Note the spike with the long expiratory phase
What does this spirometry likely indicate?
Vocal cord dysfunction
What does this spirometry likely indicate?
Asthma
What are the major SABAs?
Albuterol (MAIN ONE)
Levalbuterol (isomer of albuterol)
Most common leukotriene modifier?
Montelukast
What are the symptoms of respiratory arrest imminent?
While at rest, bute
Silent
Drowsy or confused
What are the signs of respiratory arrest imminent?
RR >30/min
Unable to recline
Paradoxical thoracoabdominal movement
Abesnt wheeze
Bradycardia