4.4- acatuge immunistaion and vaccination etc. Flashcards

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1
Q

how is active immunity developed?

A

by vaccination with antigens from infectious pathogens to create an immunological memory

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2
Q

why are adjuvants mixed with antigens from infectious pathogens?

A

to enhance the immune response generated by a vaccine

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3
Q

what do sources of antigens for vaccines include?

A

inactivated pathogen toxins
dead pathogens
parts of pathogens
weakened pathogens

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4
Q

why do vaccines undergo clinical trials ?

A

to establish their safety and effectiveness

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5
Q

name some designs of clinical trials

A

randomised, double-blind, placebo-controlled protocols

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6
Q

why are group size and replicated important when carrying out a clinching trial?

A

they can affect the reliability or results and the significance of any statistics collected

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7
Q

when does herd immunity occur?

A

when a large percentage of a population is immunised

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8
Q

what happens in herd-immunity ?

A

non-immune individuals are protected as there is a lower probability that they will come into contact with infected individuals

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9
Q

what does the herd immunity dependant on?

A

the disease, the effectiveness of the vaccine and the contact parameters s for the population

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10
Q

what is the stain of public health immunisation?

A

to establish herd immunity to a number of diseases

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11
Q

when is widespread vaccination not possible?

A

when populations are malnourished, t population is in poverty or percentage is in poverty or a percentage rejects the vaccine

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12
Q

what is influenza

A

a viral disease that a widely vaccinated against using annually developed vaccines

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13
Q

what are malaria and trypanosomiasis caused by?

A

protozoa, which are carrier by vectors and difficult to vaccinate against because they change their antigenic nature

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14
Q

what are HIV and tuberculosis examples of?

A

pathogens involved in direct attack on the immune system

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15
Q

what is HIV

A

a virus that attacks lymphocyte and the major cause of AIDS

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16
Q

what is TB

A

caused by a bacterium that survives within phagocytes and avoids immunity detection