4.3.2.1 Producing Monoclonal Antibodies Flashcards
1
Q
How are monoclonal antibodies produced?
A
- lots of clones from a single white blood cell
- means all antibodies are identical and target one specific antigen
2
Q
What is used to grow more antibodies?
A
- B-lymphocytes
3
Q
What is used to divide quickly?
A
- tumour cells
4
Q
What happens during the process of making monoclonal antibodies?
A
- antigen injected into mouse and spleen produces lymphocytes
- tumour cells taken from a lab and fused with lymphocyte to make a hybridoma
5
Q
What are hybridoma cells useful for?
A
- quickly cloning identical cells to produces same antibodies
6
Q
Why are monoclonal antibodies useful?
A
- only bind to one specific antigen so they can target one thing in body
7
Q
What is an issue with monoclonal antibodies?
A
- they cause more side effects than expected
