4. Synaptic Transmission AO1 Flashcards
What is a synapse?
Each neuron is separated from the next by a tiny gap called the synapse
How are signals within neurons transmitted?
Electrically
How are signals between neurons transmitted?
Chemically across the synapse
What happens when the electrical impulse reaches the end of a neuron?
It triggers the release of neurotransmitter from tiny sacs called synaptic vesicles
What happens after the release of the neurotransmitter?
It crosses the gap, it is taken up by the postsynaptic receptor site in the next neuron
What happens after neurotransmitter is taken up by the postsynaptic receptor site?
Chemical message is converted back into an electrical impulse and the process of electric transmission begins
What are neurotransmitters?
Chemicals that diffuse across the synapse to the next neuron in the chain
Outline a neurotransmitter
Several dozen have been identified, each has its own specific molecular structure that fits perfectly into a postsynaptic take receptor site (lock and key) - each has a specific function
Give an example of a neurotransmitter and explain its role
Serotonin - affects mood and social behaviour which is why it has been implicated as a cause of depression
What do neurotransmitters usually have?
Excitatory or inhibitory effects on the neighboring neuron
Explain adrenaline in regard to being excitatory or inhibitory
Generally excitatory, increasing positive charge of the postsynaptic neuron, making it more likely the neuron will fire
Explain serotonin in regard to being excitatory or inhibitory
Generally inhibitory, increasing the negative charge of the postsynaptic neuron, making it less likely the neuron will fire
Explain dopamine in regard to being excitatory or inhibitory
It is an unusual neurotransmitter is it is equally likely to have excitatory or inhibitory effects on the next neuron in the chain
Explain summation
Excitatory and inhibitory influences are summed and must reach certain threshold for action potential of postsynaptic neuron to be triggered
When is a postsynaptic neuron less likely to fire
If the net effect of neurotransmitter is inhibitory